MMP 1 (Interstitial Collagenase) (Native Protein)
-
Catalog number30 101 002
-
PricePlease ask
-
Size10 µg/ 200µl
-
-
Protein typeNative
-
Protein subtypeEC 3.4.24.7
-
Protein familyMatrix Metalloproteinases, matrixins
-
Protein descriptionMMP1 cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tats mediated neurotoxicity.
-
Research area interestsDiseases associated with MMP1 include Epidermolysis Bullosa Dystrophica, Ar and Pulmonary Disease, Chronic Obstructive. Among its related pathways are Pathways in cancer and PPAR signaling pathway.
-
Package formliquid
-
Tested applicationsDegaradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard
-
Other namesMatrix Metalloproteinase 1, Fibroblast Collagenase
-
Peptide sequenceMHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
-
Available target modificationNo
-
Expression systemHuman Fibroblast
-
Product Subtypefull length
-
Active formYes
-
Taguntagged
-
Contents50 mM Tris/HCl, pH 7.0, 300 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2, 0.05% NaN3, 0.05% Brij 35.
-
Protein purity>90%
-
Molecular weight52-56 kDa
-
UniProt numberP03956
-
Gene number4312
-
AbbreviationMMP1
-
Full namematrix metallopeptidase 1
-
Other desciptionHuman MMP1 is isolated from human fibroblasts.
-
PurificationMentioned in the data sheet
-
PubMed citationsSee the data sheet
-
WarningsFor Research Use only.
-
Shipping conditionsdry ice
-
Storage conditionStore at -70°C
-
Technical datasheetContact us to receive the datasheet
-
Gene target
-
Gene symbolMMP24, MMP14, MMP28, MMP17, MMP15, MMP25, MMP16
-
Short nameMMP 1 (Interstitial Collagenase) (Native Protein)
-
SpeciesHomo sapiens
-
Alternative nameMMP 1 (Interstitial Collagenase) (Native Protein)
-
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 24
-
Synonyms gene name
- matrix metalloproteinase 24 (membrane-inserted)
- matrix metallopeptidase 24 (membrane-inserted)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-08-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 14
-
Synonyms gene name
- matrix metalloproteinase 14 (membrane-inserted)
- matrix metallopeptidase 14 (membrane-inserted)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1994-11-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 28
-
Synonyms gene name
- matrix metalloproteinase 28
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-01-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 17
-
Synonyms gene name
- matrix metalloproteinase 17 (membrane-inserted)
- matrix metallopeptidase 17 (membrane-inserted)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1996-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 15
-
Synonyms gene name
- matrix metalloproteinase 15 (membrane-inserted)
- matrix metallopeptidase 15 (membrane-inserted)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1996-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 25
-
Synonyms gene
-
Synonyms gene name
- matrix metalloproteinase 25
- matrix metallopeptidase-like 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-12-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namematrix metallopeptidase 16
-
Synonyms gene
-
Synonyms gene name
- matrix metalloproteinase 16 (membrane-inserted)
- chromosome 8 open reading frame 57
- matrix metallopeptidase 16 (membrane-inserted)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1996-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- M10 matrix metallopeptidases
-
VEGA ID