MLN8237

• Catalog number
  2718-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-benzoic acid; Alisertib
• Description
  MLN8237 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ =1.2 nM). It displays >200-fold higher selectivity for Aurora kinase A over Aurora kinase B. Displays antineoplastic activity.
• CAS Number
  1028486-01-2
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₇H₂₀ClFN₄O₄
• Molecular Weight
  518.9
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent Aurora kinase A inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• PubChem CID
  24771867
• PubChem CID Link
• SMILES
  COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC
• InChi
  InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11,13H,12H2,1-2H3,(H,34,35)(H,31,32,33)
• InChi Key
  ZLHFILGSQDJULK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  MLN8237  
• Short name
  MLN8237
• Alternative name
  MLN8237

Similar products