ML130

• Catalog number
  1974-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  1-Tosyl-1H-benzo[d]imidazol-2-amine; Nodinitib-1
• Description
  Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC₅₀ = 0.56±0.04 µM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-⍺-induced NF-kB activation.
• CAS Number
  799264-47-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₃N₃O₂S
• Molecular Weight
  287.34
• Cell Permeable
  Yes
• Purity
  ≥97% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from light and air
• Tag Line
  A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD04322367
• PubChem CID
  1088438
• PubChem CID Link
• SMILES
  CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N
• InChi
  InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
• InChi Key
  SRFABRWQVPCPRG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  ML130  
• Short name
  ML130
• Alternative name
  ML130

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