MKL1, ID (MKL1, KIAA1438, MAL, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A)

• Catalog number
  MBS6000684
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  MKL1   MKL1   KIAA1438   MAL   MKL/myocardin-like   protein   Megakaryoblastic   leukemia   protein   Megakaryocytic   acute   leukemia   protein   Myocardin-related   transcription   factor  
• Gene symbol
  MRTFA, TIRAP, MAL
• Short name
  MKL1, ID (MKL1, KIAA1438, MAL, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin- transcription factor A)
• Alternative name
  megakaryoblastic leukemia (translocation) 1, ID (megakaryoblastic leukemia (translocation) 1, KIAA1438, mal, T-cell differentiation protein, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A)
• Alternative to gene target
  megakaryoblastic leukemia (translocation) 1, MKL1 and IDBG-8802 and ENSG00000196588 and 57591, leucine zipper domain binding, nuclei, Mkl1 and IDBG-164431 and ENSMUSG00000042292 and 223701, MKL1 and IDBG-641821 and ENSBTAG00000002630 and 509011
• Virus
  leukemia

Gene info

• Identity
  HGNC:14334
• Gene
  MRTFA
• Long gene name
  myocardin related transcription factor A
• Synonyms gene
  • MKL1
• Synonyms gene name
  • megakaryoblastic leukemia (translocation) 1
• Synonyms
  • KIAA1438
  • MAL
  • MRTF-A
  • BSAC
  • MKL
• Synonyms name
  • megakaryocytic acute leukemia
  • basic, SAP and coiled-coil domain
• GenBank acession
  • AB037859
• Locus
  22q13.1-q13.2
• Discovery year
  2001-05-10
• Entrez gene record
  57591
• Pubmed identfication
  • 11431691
  • 12019265
  • 14970199
• RefSeq identity
  • NM_020831
• Classification
  • Myocardin family
• VEGA ID
  OTTHUMG00000151146
• Locus Specific Databases
  • LRG_1427

Gene info

• Identity
  HGNC:17192
• Gene
  TIRAP
• Long gene name
  TIR domain containing adaptor protein
• Synonyms gene name
  • Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
• Synonyms
  • Mal
  • wyatt
• Synonyms name
  • MyD88 adapter-like
• GenBank acession
  • AF378129
• Locus
  11q24.2
• Discovery year
  2003-06-05
• Entrez gene record
  114609
• Pubmed identfication
  • 11526399
  • 11544529
• RefSeq identity
  • NM_148910
• Classification
  • TIR domain containing
• VEGA ID
  OTTHUMG00000140373

Gene info

• Identity
  HGNC:6817
• Gene
  MAL
• Long gene name
  mal, T cell differentiation protein
• Synonyms gene name
  • mal, T-cell differentiation protein
• Synonyms
  • MVP17
  • VIP17
• Synonyms name
  • MyD88-adapter-like
  • myelin and lymphocyte protein
• Locus
  2q11.1
• Discovery year
  1986-01-01
• Entrez gene record
  4118
• Pubmed identfication
  • 12072368
• RefSeq identity
  • NM_002371
• Classification
  • MARVEL domain containing
• VEGA ID
  OTTHUMG00000132011

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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