MIP-1beta, murine recombinant

Synonyms

Macrophage Inflammatory Protein-1 β, CCL4, ACT-2
Alternative_names

Macrophage Inflammatory Protein-1 β, CCL4, ACT-2, G-26 T-lymphocyte-secreted protein, HC21, Lymphocyte activation gene 1 protein, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2
Description

Chemoattractant for NK cells, monocytes and other immune cells
Recombinant

Yes
Source

E. coli
Purity by SDS PAGE

≥98%
Assay

SDS-PAGE
Purity

≥98%
Biological activity

Determined by its ability to chemoattract human blood monocytes using a concentration of 20-100 ng/ml.
Results

20-100 ng/ml
Molecular Weight

7.8 kDa
Storage Temp

-20°C
Shipping

Blue ice
Shelf Life

12 months
Appearance

Lyophilized protein
Physical form description

Sterile filtered and lyophilized with no additives
Reconstitution Instructions

Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers
Background Information

Murine macrophage inflammatory protein-1 β (MIP-1β) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
Handling

Centrifuge the vial prior to opening.
Usage

For Research Use Only! Not to be used in humans
Datasheet
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

MIP-1beta murine
Gene symbol

MIPEP, TNPO1, MIP, CCL26, TRAPPC2B, CCL15, TRAF3IP1, MAFIP, TRAPPC2, CCL23
Short name

MIP-1beta, murine recombinant
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Alternative name

MIP-1beta, murine Rec.
Alternative technique

rec

Identity

HGNC:6401
Gene

TNPO1
Long gene name

transportin 1
Synonyms gene
- KPNB2
Synonyms gene name
- karyopherin (importin) beta 2
Synonyms
- MIP
- TRN
- IPO2
- MIP1
Synonyms name
- importin 2
GenBank acession
- U70322
Locus

5q13.2
Discovery year

1997-04-21
Entrez gene record

3842
Pubmed identfication
- 8808633
- 9144189
RefSeq identity
- NM_002270
Classification
- Importins
- Armadillo like helical domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000100967

Identity

HGNC:10625
Gene

CCL26
Long gene name

C-C motif chemokine ligand 26
Synonyms gene
- SCYA26
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 26
- chemokine (C-C motif) ligand 26
Synonyms
- MIP-4alpha
- eotaxin-3
- IMAC
- MIP-4a
- TSC-1
Synonyms name
GenBank acession
- AF124601
Locus

7q11.23
Discovery year

1999-06-09
Entrez gene record

10344
Pubmed identfication
- 10373330
RefSeq identity
- NM_006072
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000130403

Identity

HGNC:10710
Gene

TRAPPC2B
Long gene name

trafficking protein particle complex subunit 2B
Synonyms gene
- SEDLP
- TRAPPC2P1
Synonyms gene name
- spondyloepiphyseal dysplasia, late, pseudogene
- trafficking protein particle complex 2 pseudogene 1
- trafficking protein particle complex 2B
Synonyms
- SEDLP1
- MIP-2A
Locus

19q13.43
Discovery year

2000-01-20
Entrez gene record

10597
Pubmed identfication
- 11134351
- 24098805
RefSeq identity
- NM_001355204
VEGA ID

OTTHUMG00000183279

Identity

HGNC:10613
Gene

CCL15
Long gene name

C-C motif chemokine ligand 15
Synonyms gene
- SCYA15
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 15
- chemokine (C-C motif) ligand 15
Synonyms
- HCC-2
- NCC-3
- SCYL3
- MIP-5
- Lkn-1
- MIP-1d
- HMRP-2B
Synonyms name
GenBank acession
- AF031587
Locus

17q12
Discovery year

1997-02-11
Entrez gene record

6359
Pubmed identfication
- 8661057
RefSeq identity
- NM_004167
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000188406

Identity

HGNC:23068
Gene

TRAPPC2
Long gene name

trafficking protein particle complex subunit 2
Synonyms gene
- SEDL
Synonyms gene name
- spondyloepiphyseal dysplasia, late
- trafficking protein particle complex 2
Synonyms
- TRS20
- SEDT
- MIP-2A
- ZNF547L
- hYP38334
GenBank acession
- AF157061
Locus

Xp22.2
Discovery year

2005-01-26
Entrez gene record

6399
Pubmed identfication
- 14597397
RefSeq identity
- NM_014563
Classification
- Trafficking protein particle complex subunits
VEGA ID

OTTHUMG00000021157

Identity

HGNC:10622
Gene

CCL23
Long gene name

C-C motif chemokine ligand 23
Synonyms gene
- SCYA23
Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 23
- chemokine (C-C motif) ligand 23
Synonyms
- Ckb-8
- MPIF-1
- MIP-3
- CKb8
GenBank acession
- U58913
Locus

17q12
Discovery year

1997-11-14
Entrez gene record

6368
Pubmed identfication
- 9104803
- 10409433
RefSeq identity
- NM_005064
- NM_145898
Classification
- Chemokine ligands
VEGA ID

OTTHUMG00000188409

Name

Urine Specimen Collection
Concept

Scope note: Methods or procedures used to obtain samples of URINE.
Tree numbers
- E01.370.225.998.762
- E05.200.998.762
Qualifiers

ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data