MGST1 Antibody

• Catalog number
  R31937
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MGST1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the MGST1 antibody should be determined by the researcher.
• Intented use
  This MGST1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P10620
• Purity
  Antigen affinity
• Description
  Microsomal glutathione S-transferase 1 is an enzyme that in humans is encoded by the MGST1 gene. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.
• Immunogen
  Amino acids KVFANPEDCVAFGKGENAKKYLRTDDRVERVRRA of human MGST1 were used as the immunogen for the MGST1 antibody.
• Storage
  After reconstitution, the MGST1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MGST1  
• Gene symbol
  MGST1, PTGES
• Short name
  Anti-MGST1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to MGST1
• Alternative technique
  antibodies
• Alternative to gene target
  microsomal glutathione S-transferase 1, GST12 and MGST and MGST-I, MGST1 and IDBG-21764 and ENSG00000008394 and 4257, glutathione binding, nuclei, Mgst1 and IDBG-195593 and ENSMUSG00000008540 and 56615, MGST1 and IDBG-639137 and ENSBTAG00000008541 and 493719

Gene info

• Identity
  HGNC:7061
• Gene
  MGST1
• Long gene name
  microsomal glutathione S-transferase 1
• Synonyms gene
  • GST12
• Synonyms
  • MGST-I
• GenBank acession
  • U46494
• Locus
  12p12.3
• Discovery year
  1989-05-24
• Entrez gene record
  4257
• RefSeq identity
  • NM_145791
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000168816

Gene info

• Identity
  HGNC:9599
• Gene
  PTGES
• Long gene name
  prostaglandin E synthase
• Synonyms gene
  • MGST1L1
• Synonyms
  • MGST-IV
  • PIG12
  • MGST1-L1
  • TP53I12
• Synonyms name
  • microsomal glutathione S-transferase 1-like 1
  • tumor protein p53 inducible protein 12
  • p53-induced gene 12
  • microsomal prostaglandin E synthase-1
  • glutathione S-transferase 1-like 1
  • MGST1-like 1
• GenBank acession
  • AF010316
• Locus
  9q34.11
• Discovery year
  1999-05-06
• Entrez gene record
  9536
• Pubmed identfication
  • 9305847
  • 10091672
• RefSeq identity
  • NM_004878
• VEGA ID
  OTTHUMG00000020791

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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