MEK5(Ser311+Thr315) Antibody

• Catalog number
  bs-5430R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MEK5(Ser311+Thr315) Primary Polyclonal Antibody
• Also known as
  MEK5(Ser311+Thr315) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MEK5 Ser311+Thr315
• Specificity
  This is a highly specific antibody against MEK5 Ser311+Thr315.
• Modification s
  Phosphorylation
• Modification site s
  Ser311+Thr315
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human MEK5 around the phosphorylation site of Ser311+Thr315
• Gene ID number
  5607
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family, (MAP kinase kinase family). It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, and not with another MAP kinase like P38. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). It is not phosphorylated by RAFA, RAFB or RAFC and it may interact with GTPases such as CDC42. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MAP2K5 phospho S311/T315; Dual specicity mitogen activated protein kinase kinase 5; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPKK5; PRKMK5; EC 2.7.12.2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MEK5   Ser311+Thr315  
• Gene symbol
  MAP2K5
• Short name
  Anti-MEK5 Ser311+Thr315
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MEK5(Ser311+Thr315) Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6845
• Gene
  MAP2K5
• Long gene name
  mitogen-activated protein kinase kinase 5
• Synonyms gene
  • PRKMK5
• Synonyms
  • MEK5
  • MAPKK5
  • HsT17454
• GenBank acession
  • U25265
• Locus
  15q23
• Discovery year
  1997-11-11
• Entrez gene record
  5607
• Pubmed identfication
  • 7759517
• RefSeq identity
  • NM_145162
• Classification
  • Mitogen-activated protein kinase kinases
• VEGA ID
  OTTHUMG00000133264

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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