MCP-1 Recombinant Protein

• Catalog number
  40-410
• Price
  Please ask
• Size
  0.002 mg, 0.01 mg

• About recombinant protein
  The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Other name of the recombinant
  MCP-1, Scya2, Sigje, Je, Mcp1, C-C motif chemokine 2, Immediate-early serum-responsive protein JE, MCP-1
• Recombinant in
  E. coli
• SEQUENCE
  QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEWV QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLTHKS EANASTLFST TTSSTSVEVT SMTEN
• Activity
  Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 10.0 - 100.0 ng/mL.
• Keep at
  The lyophilized MCP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted MCP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing MCP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  13928714
• Accession nr
  NP_113718.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Rat
• Vial
  Lyophilized
• NCBI ID
  24770
• Gene name
  chemokine (C-C motif) ligand 2
• Source
  Rattus norvegicus
• Uniprot
  P14844
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  MCP-1   Protein  
• Gene symbol
  Ccl2
• Short name
  MCP-1 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  MCP-1 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:10618
• Gene
  CCL2
• Long gene name
  C-C motif chemokine ligand 2
• Synonyms gene
  • SCYA2
• Synonyms gene name
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
  • chemokine (C-C motif) ligand 2
• Synonyms
  • MCP1
  • MCP-1
  • MCAF
  • SMC-CF
  • GDCF-2
  • HC11
  • MGC9434
• Synonyms name
  • monocyte chemotactic protein 1, homologous to mouse Sig-je
  • monocyte chemoattractant protein-1
  • monocyte chemotactic and activating factor
  • monocyte secretory protein JE
  • small inducible cytokine subfamily A (Cys-Cys), member 2
• GenBank acession
  • BC009716
• Locus
  17q12
• Discovery year
  1990-07-05
• Entrez gene record
  6347
• Pubmed identfication
  • 2004761
• RefSeq identity
  • NM_002982
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132887

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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