Maspin Recombinant Protein

• Catalog number
  40-232
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells. Recombinant human Maspin is a 42.2 kDa non-glycosylated protein containing 375 amino acid residues.
• Other name of the recombinant
  PI5, maspin, PI5, Serpin B5, Maspin, PI-5
• Recombinant in
  E. coli
• SEQUENCE
  MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP
• Keep at
  The lyophilized Maspin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Maspin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Maspin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  167860126
• Accession nr
  NP_002630.2
• Pureity
  Greater than 97% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  5268
• Gene name
  serpin peptidase inhibitor, clade B (ovalbumin), member 5
• Source
  Homo sapiens
• Uniprot
  P36952
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Maspin   Protein  
• Gene symbol
  SERPINB5
• Short name
  Maspin Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Maspin Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8949
• Gene
  SERPINB5
• Long gene name
  serpin family B member 5
• Synonyms gene
  • PI5
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
  • serpin peptidase inhibitor, clade B (ovalbumin), member 5
• Synonyms
  • maspin
• Synonyms name
  • protease inhibitor 5 (maspin)
• GenBank acession
  • U04313
• Locus
  18q21.33
• Discovery year
  1994-06-20
• Entrez gene record
  5268
• Pubmed identfication
  • 8290962
  • 7724531
  • 16720730
  • 24172014
• RefSeq identity
  • NM_002639
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000141307

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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