NFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 488

• Catalog number
  bs-0074R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  NFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-NFkB Inducing Kinase NIK PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  NFkB Inducing Kinase NIK
• Specificity
  This is a highly specific antibody against NFkB Inducing Kinase NIK.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  900-947/947
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIK
• Gene ID Number
  9020
• Swiss Prot
  Q99558
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P1, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  HS; NIK; HSNIK; FTDCR1B; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK; MAP3K14
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NFkB Inducing Kinase NIK has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
• French translation
  anticorps

• Gene target
  NFkB   Kinase   NIK  
• Gene symbol
  MAP4K4, MAP3K14
• Short name
  Anti-NFkB Inducing Kinase NIK
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  NFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6866
• Gene
  MAP4K4
• Long gene name
  mitogen-activated protein kinase kinase kinase kinase 4
• Synonyms
  • HGK
  • NIK
  • FLH21957
• Synonyms name
  • HPK/GCK-like kinase
  • hepatocyte progenitor kinase-like/germinal center kinase-like kinase
• GenBank acession
  • AF096300
• Locus
  2q11.2
• Discovery year
  1999-09-07
• Entrez gene record
  9448
• Pubmed identfication
  • 9890973
  • 9734811
  • 9135144
• RefSeq identity
  • NM_004834
• Classification
  • Mitogen-activated protein kinase kinase kinase kinases
• VEGA ID
  OTTHUMG00000155394

Gene info

• Identity
  HGNC:6853
• Gene
  MAP3K14
• Long gene name
  mitogen-activated protein kinase kinase kinase 14
• Synonyms
  • NIK
  • HSNIK
  • FTDCR1B
  • HS
• Synonyms name
  • serine/threonine protein-kinase
• GenBank acession
  • Y10256
• Locus
  17q21.31
• Discovery year
  2000-08-11
• Entrez gene record
  9020
• Pubmed identfication
  • 9020361
• RefSeq identity
  • NM_003954
• Classification
  • Mitogen-activated protein kinase kinase kinases
• VEGA ID
  OTTHUMG00000180364
• Locus Specific Databases
  • LRG_1222

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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