MALT1

• Catalog number
  GEN438138
• Price
  Please ask
• Size
  100ug

• Also known as
  MALT1
• Other names
  mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT lymphoma-associated translocation; mucosa associated lymphoid tissue lymphoma translocation gene 1; MALT lymphoma-associated translocation; Paracaspase
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  MALT1
• Gene name synonims
  N/A
• Other gene names
  MALT1; MALT1; MLT; MLT1; IMD12; MLT
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  SPM578
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  MALT1  
• Gene symbol
  MALT1-AS1, MALT1
• Short name
  MALT1
• Alternative name
  Anti-MALT1
• Alternative to gene target
  mucosa associated lymphoid tissue lymphoma translocation gene 1, IMD12 and MLT and MLT1, MALT1 and IDBG-3930 and ENSG00000172175 and 10892, protein self-association, nuclei, Malt1 and IDBG-154592 and ENSMUSG00000032688 and 240354, MALT1 and IDBG-644866 and ENSBTAG00000027916 and 504994

Gene info

• Identity
  HGNC:55306
• Gene
  MALT1-AS1
• Long gene name
  MALT1 antisense RNA 1
• Locus
  18q21.32
• Discovery year
  2020-10-16
• Entrez gene record
  101927322
• RefSeq identity
  • NR_164150
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6819
• Gene
  MALT1
• Long gene name
  MALT1 paracaspase
• Synonyms gene
  • MLT
• Synonyms gene name
  • mucosa associated lymphoid tissue lymphoma translocation gene 1
• Synonyms
  • PCASP1
• Synonyms name
  • MALT1 protease
  • paracaspase 1
• Locus
  18q21.32
• Discovery year
  1999-08-02
• Entrez gene record
  10892
• Pubmed identfication
  • 10339464
  • 10406266
  • 10523859
  • 11090634
  • 26377317
• RefSeq identity
  • NM_006785
• Classification
  • Immunoglobulin like domain containing
  • CBM complex
• VEGA ID
  OTTHUMG00000132761
• Locus Specific Databases
  • LRG_1221

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