MADCAM1 Antibody

• Catalog number
  R31195
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MADCAM1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, IHC-F
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the MADCAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MADCAM1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q13477
• Purity
  Antigen affinity
• Description
  Mucosal Vascular Addressin Cell Adhesion Molecule 1 is a protein that in humans is encoded by the MADCAM1 gene. By PCR-based analysis of somatic cell hybrids, Leung et al.(1997) mapped the gene to chromosome 19. The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1(alpha4 / beta7), L-selectin, and VLA-4(alpha4/beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.
• Immunogen
  An amino acid sequence from the middle region of human MADCAM1 (EEPQGDEDVLFRVTERWR) was used as the immunogen for this MADCAM1 antibody.
• Storage
  After reconstitution, the MADCAM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MADCAM1  
• Gene symbol
  MADCAM1, MADCAM1-AS1
• Short name
  Anti-MADCAM1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to MADCAM1
• Alternative technique
  antibodies
• Alternative to gene target
  mucosal vascular addressin cell adhesion molecule 1, MACAM1, MADCAM1 and IDBG-12208 and ENSG00000099866 and 8174, protein binding, Plasma membranes, Madcam1 and IDBG-170375 and ENSMUSG00000020310 and 17123, BT.46202 and IDBG-645471 and ENSBTAG00000039355 and 527275,789849

Gene info

• Identity
  HGNC:6765
• Gene
  MADCAM1
• Long gene name
  mucosal vascular addressin cell adhesion molecule 1
• Synonyms
  • MACAM1
• Synonyms name
  • mucosal addressin cell adhesion molecule-1
• GenBank acession
  • U43628
• Locus
  19p13.3
• Discovery year
  2000-02-11
• Entrez gene record
  8174
• Pubmed identfication
  • 9162097
  • 8609404
• RefSeq identity
  • NM_130760
• Classification
  • Immunoglobulin like domain containing
  • Ig-like cell adhesion molecule family
• VEGA ID
  OTTHUMG00000180548

Gene info

• Identity
  HGNC:55315
• Gene
  MADCAM1-AS1
• Long gene name
  MADCAM1 antisense RNA 1
• Locus
  19p13.3
• Discovery year
  2020-10-19
• Entrez gene record
  105372232
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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