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Also known as
Epidermal Growth Factor Receptor (EGFR)
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Other names
epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
EGFR
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Gene name synonims
N/A
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Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1
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Clonality
Monoclonal
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Immunoglobulin isotype
Rabbit IgG
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Clone
SP84
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Host organism
Rabbit (Oryctolagus cuniculus)
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Species reactivity
Tested: Human (Homo sapiens) Expected from sequence similarity: Bovine, Dog, Frog, Mouse (Mus musculus), Pig, Rat (Rattus norvegicus) ; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. DO NOT FREEZE. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.
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Tested applications
Immunohistochemistry (IHC) (Paraffin), Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbol
EGFR-AS1, EGILA, EGFR, RHBDF1
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Short name
Anti- Epidermal Growth Factor Receptor (EGFR) MAb (Clone SP84)
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Technique
anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
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Species
Human, Humans
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Alternative name
Anti-Rabbit Anti-Human Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody (Clone SP84)
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Alternative technique
antibodies
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Alternative to gene target
epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Clone name
SP84
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