mAb Anti Human PD-L1 clone 12B4, Tracer (Biotin) (Monoclonal)
-
Catalog numberMBS590085
-
PricePlease ask
-
Size5x0.1 mL
-
-
Products_typeAntibody
-
Products_short_name[PD-L1]
-
Products_name_syn[mAb anti-Human PD-L1; Mouse monoclonal antibody (mAb) to human programmed death-ligand 1 (PD-L1); mouse mAb to B7H1; mouse mAb to human CD274, Tracer (Biotin Labeled); Biotin conjugated Mouse monoclonal antibody (mAb) to human programmed death-ligand 1 (PD-L1)]
-
Other_names[programmed cell death 1 ligand 1 isoform c; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; CD274 molecule; B7 homolog 11 PublicationManual assertion based on opinion iniRef.1"B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion."Dong H., Zhu G., Tamada K., Chen L.Nat. Med. 5:1365-1369(1999) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, INDUCTION.]
-
Products_gene_name[PD-L1]
-
Other_gene_names[CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; PD-L12 PublicationsManual assertion based on opinion iniRef.10; PDCD1 ligand 1; Programmed death ligand 1; B7-H11 PublicationManual assertion based on opinion iniRef.1]
-
ClonalityMonoclonal
-
Clone[12B4]
-
ReactivityHuman. Others not tested.
-
SpecificityReactive with human programmed death-ligand 1 (PD-L1).
-
PurityProtein G Affinity Purified
-
FormLyophilized from a solution in 0.01M PBS, pH 7.2
-
Storage_stabilityStore at -20 degree C. Avoid repeated freeze/thaw cycles after reconstitution.
-
Tested_applicationELISA (EIA)
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
-
PropertiesBiotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
ConjugationBiotinylated
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
Gene target
-
Gene symbolCD274, ENPP2, MTA2, MICALL1, IGKV1-16, ZBTB4, UCHL1, COLEC10, PDCD1, FAM71F1
-
Short namemAb Anti PD-L1 clone 12B4, Tracer ( ) (Monoclonal)
-
Techniqueanti human, anti, antibody to, anti human antibodies, Monoclonals or monoclonal antibodies
-
HostMouse
-
IsotypeIgG1,k
-
LabelBiotin
-
SpeciesHuman, Humans
-
Alternative namemonoclonal antibody to H. sapiens PD-L1 clonality 12B4, Tracer (biotinilated) (monoclonal)
-
Alternative techniqueantibodies
-
Clone name12B4
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD274 molecule
-
Synonyms gene
-
Synonyms gene name
- programmed cell death 1 ligand 1
- CD274 antigen
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 2
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1995-08-10
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemetastasis associated 1 family member 2
-
Synonyms gene
-
Synonyms gene name
- metastasis associated gene family, member 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-05-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- GATA zinc finger domain containing
- NuRD complex subunits
- Myb/SANT domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameMICAL like 1
-
Synonyms gene name
- MICAL-like 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2006-11-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- LIM domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1-16
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin kappa locus at 2p11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namezinc finger and BTB domain containing 4
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-12-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- BTB domain containing
- Zinc fingers C2H2-type
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameubiquitin C-terminal hydrolase L1
-
Synonyms gene
-
Synonyms gene name
- ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-07-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Ubiquitin C-terminal hydrolases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecollectin subfamily member 10
-
Synonyms gene name
- collectin sub-family member 10 (C-type lectin)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-11
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Collectins
- C-type lectin domain containing
- Complement system activation components
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprogrammed cell death 1
-
Synonyms gene
-
Synonyms gene name
- systemic lupus erythematosus susceptibility 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-05-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namefamily with sequence similarity 71 member F1
-
Synonyms gene
-
Synonyms gene name
- family with sequence similarity 137, member A
- family with sequence similarity 71, member F1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2007-07-24
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data