Lysophosphatidic Acid Receptor 1 (EDG2) - Control Lysate
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Catalog numberX1218C
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PricePlease ask
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Size100uL
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CategoryOther Reagents
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Long descriptionEndothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, also known as lysophospholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca2+]i by augmenting phospholipase C through Gq/11 and beta/gamma dimers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.
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Antibody come fromn/a
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Other descriptionProvided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol.
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Clonenot specified
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Antigen antibody binding interactionLysophosphatidic Acid Receptor 1 (EDG2) - Control Lysate
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Antibody is raised insee techfile
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Antibody s reacts withsee techfile
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Antibody s reacts with these speciesThis antibody doesn't cross react with other species
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Antibody s specificityNo Data Available
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ApplicationWestern Blot
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Antibody s suited forFor use as a positive control with Exalpha's EDG2 (LPA1) polyclonal antibody (Cat. No. C174P) for Western blot analysis.
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Storage-20ºC
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Relevant referencesno information yet
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Protein numbersee ncbi
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WarningsThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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DescriptionIsotype or positive controls by peptides, antibodies and deactivated samples. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolBUD31, LPAR1
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Short nameLysophosphatidic Acid Receptor 1 (EDG2) - Control Lysate
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TechniqueControl, controls
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Isotypenot specified
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Labelunlabeled
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Alternative nameLysophosphatidic Acid Receptor 1 (EDG2) - reference Lysate
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Alternative techniquecontrols
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Tissuecontrol, lysate
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Viruslysate
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Gene info
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Identity
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Gene
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Long gene nameBUD31 homolog
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Synonyms gene
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Synonyms gene name
- G10 maternal transcript homolog (Xenopus laevis)
- BUD31 homolog (yeast)
- BUD31 homolog (S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-03-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Spliceosomal C complex
- NTC associated proteins
- Spliceosomal B complex
- Spliceosomal Bact complex
- Spliceosomal P complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysophosphatidic acid receptor 1
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Synonyms gene
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Synonyms gene name
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-05-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Lysophosphatidic acid receptors
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VEGA ID
