Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha) Antibody

  • Catalog number
    GEN608415
  • Price
    Please ask
  • Size
    100ul
  • Also known as
    Lymphoid Enhancer Factor 1
  • Other names
    lymphoid enhancer-binding factor 1 isoform 1; Lymphoid enhancer-binding factor 1; lymphoid enhancer-binding factor 1; TCF1-alpha; T cell-specific transcription factor 1-alpha; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
  • Gene name synonims
    LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
  • Other gene names
    LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG
  • Clone
    7H38
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes endogenous level of total human LEF1 protein at ~25-58kD. Does not recognize the dominant negative forms of LEF1 generated by an alternative promoter. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Supernatant
  • Form Appearance
    Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, < 0.02% sodium azide, 50% glycerol.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested applications
    Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
  • Description
    The Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha) Antibody is a α- or alpha protein sometimes glycoprotein present in blood. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    LEF1-AS1, LEF1, HNF1A
  • Short name
    Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha)
  • Alternative technique
    antibodies
  • Alternative to gene target
    lymphoid enhancer-binding factor 1, LEF1 and IDBG-33529 and ENSG00000138795 and 51176, DNA binding, nuclei, Lef1 and IDBG-194292 and ENSMUSG00000027985 and 16842, LEF1 and IDBG-640560 and ENSBTAG00000006844 and 535399
  • Tissue
    cell
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    lymphoid enhancer binding factor 1
  • Synonyms gene name
    • lymphoid enhancer-binding factor 1
  • Synonyms
  • Locus
  • Discovery year
    1991-06-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • TCF/LEF transcription factor family
    • Wnt enhanceosome complex
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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