LRIG1, Lig-1 (40 µg, HRP-conjugated)
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Catalog number
AS06 148-HRP
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Price
Please ask
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Size
40 µg
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Available ordering format
Liquid in PBS pH 7.4, BSA, conjugated to HRP
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Immunogen
KLH-conjugated synthetic peptide; the peptide corresponds to part of the cytoplasmic tail (C-terminal part) of the protein, not the ectodomain
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Raised in
Rabbit
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Clonality
Polyclonal
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Clone
Polyclonal
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Purification
Affinity purified IgG
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How to reconstitute
See included datasheet or contact our support service
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Storage condition
Store at +4°C for 12-18 months. A preservative may be added for long time storage up to 2 years.
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Verified applications
Western blot (WB), immunolocalization (IL)
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Connected products
AS06 156 | anti-LRIG1 hen antibodySecondary antibodies
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Recommended dilutions for use
1 µg/ml (WB), 1: 100 (IL)
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Molecular weight expected аpparent
143 kDa
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Verified reactivity
human, mice
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Possible reactivity
human
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No reactivity
no confirmed exceptions from predicted reactivity known in the moment
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Supplementary information
immunoblotting demonstrated LRIG1 protein in tissue lysates from normal human prostate, mammary epithelial cells, ileum, stomach, lung, and cerebral cortex
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References
Refer to PubMed
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Scientific context
LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a a tumour suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
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Notes
Peptide used to elicit Lrig1 antibody is not conserved in Lrig3 protein.
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Protein number
Q96JA1
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TAIR number
Refer to NCBI
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Properties
HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
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Conjugation
HRP Conjugated
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Gene target
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Gene symbol
LRIG1
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Short name
LRIG1, Lig-1 (40 µg, -conjugated)
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Technique
antibody Conjugates
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Label
HRP
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Alternative name
leucine-rich repeats and immunoglobulin-like domains 1, Lig-1 (40 µg, horseradish peroxidase-coupled)
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Alternative to gene target
leucine-rich repeats and immunoglobulin-like domains 1, LIG-1 and LIG1, LRIG1 and IDBG-43579 and ENSG00000144749 and 26018, protein binding, Plasma membranes, Lrig1 and IDBG-171701 and ENSMUSG00000030029 and 16206, LRIG1 and IDBG-645083 and ENSBTAG00000010360 and 505750
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Gene info
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