LOX Antibody / Lysyl Oxidase

  • Catalog number
    R32045
  • Price
    Please ask
  • Size
    0.1mg
  • Category
    Antibody
  • Concentration
    0.5mg/ml if reconstituted with 0.2ml sterile DI water
  • Form
    Antigen affinity purified
  • Conjugation
    Unconjugated
  • Clone
    Polyclonal antibody
  • Recognised antigen
    LOX / Lysyl Oxidase
  • Host animal
    Rabbit (Oryctolagus cuniculus)
  • Clonality
    Polyclonal (rabbit origin)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
  • Tested applications
    WB, ELISA
  • Recommended dilutions
    Western blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml
  • Notes
    Optimal dilution of the LOX antibody should be determined by the researcher.
  • Intented use
    This LOX antibodyis to be used only for research purposes and not for diagnostics..
  • Uniprot
    P28300
  • Purity
    Antigen affinity
  • Description
    Lysyl oxidase, also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
  • Immunogen
    Amino acids AEENCLASTAYRADVRDYDHRVLLRFPQR of human Lysyl Oxidase were used as the immunogen for the LOX antibody.
  • Storage
    After reconstitution, the LOX antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
  • Properties
    If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    LOX   Lysyl   Oxidase  
  • Gene symbol
    LOX, ALOX5, ALOX12B, ALOX12, ALOX15, ALOX15B, ALOXE3, OLR1
  • Short name
    Anti-LOX / Lysyl Oxidase
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Antibodies to LOX / Lysyl Oxidase
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    arachidonate 15-lipoxygenase type B
  • Synonyms gene name
    • arachidonate 15-lipoxygenase, second type
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-07-22
  • Entrez gene record
    247
  • Pubmed identfication
  • Classification
    • Arachidonate lipoxygenases
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    oxidized low density lipoprotein receptor 1
  • Synonyms gene name
    • oxidised low density lipoprotein (lectin-like) receptor 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1998-01-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • C-type lectin domain containing
    • Scavenger receptors
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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