Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L Antibody

• Catalog number
  GEN608234
• Price
  Please ask
• Size
  100ug

• Also known as
  Lissencephaly-1
• Other names
  Lissencephaly-1, isoform F; Lissencephaly-1 homolog; CG8440 gene product from transcript CG8440-RE; Lissencephaly-1, isoform E; CG8440-PE; Lis-1-PE; lissencephaly-1; Paf-AHbeta; platelet-activating factor acetylhydrolase Ib beta-subunit homolog; Lissencephaly-1, isoform D; CG8440-PD; Lis-1-PD; Lissencephaly-1, isoform A; CG8440-PA; Lis-1-PA; Lissencephaly-1, isoform C; CG8440-PC; Lis-1-PC; Lissencephaly-1, isoform B; CG8440-PB; Lis-1-PB; Lissencephaly-1, isoform F; CG8440-PF; Lis-1-PF; Lissencephaly-1; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Lis-1; Lis-1; CG8440; D-Lis1; Dlis-1; DLis-1; DLIS-1; dLis1; Dlis1; DLis1; DLIS1; DmelCG8440; DmLIS1; l(2)k13209; l(2R)W8; Lis 1; lis-1; LIS-1; lis1; Lis1; n(2)k11702; Lis1
• Gene name synonims
  Lis-1; Lis-1; CG8440; D-Lis1; Dlis-1; DLis-1; DLIS-1; dLis1; Dlis1; DLis1; DLIS1; DmelCG8440; DmLIS1; l(2)k13209; l(2R)W8; Lis 1; lis-1; LIS-1; lis1; Lis1; n(2)k11702; Lis1
• Other gene names
  Lis-1; Lis-1; CG8440; D-Lis1; Dlis-1; DLis-1; DLIS-1; dLis1; Dlis1; DLis1; DLIS1; DmelCG8440; DmLIS1; l(2)k13209; l(2R)W8; Lis 1; lis-1; LIS-1; lis1; Lis1; n(2)k11702; Lis1
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  9G377
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human Lissencephaly-1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by affinity chromatography.
• Form Appearance
  Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
• Concentration
  N/A
• Storage and shipping
  Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L Antibody is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Lissencephaly-1   LIS-1   MDCR   Miller-Dieker   Syndrome   MDS   PAF   Acetylhydrolase   45kD   Subunit   PAFAH   45kD   PAFAH   alpha   PAFAH1B1   Platelet   Activating   Factor   Acetylhydrolase   Isoform   alpha   Subunit   PAFAHA   SBH   Subcortical   Band   Heterotopia   ILS   Isolated  
• Gene symbol
  PAFAH1B1, PLA2G7, PEX2, PCLAF, PEX6, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
• Short name
  Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L
• Alternative technique
  antibodies
• Alternative to gene target
  platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa), LIS1 and LIS2 and MDCR and MDS and PAFAH, PAFAH1B1 and IDBG-16417 and ENSG00000007168 and 5048, phosphoprotein binding, nuclei, Pafah1b1 and IDBG-198862 and ENSMUSG00000020745 and 18472, PAFAH1B1 and IDBG-633101 and ENSBTAG00000016806 and 282513
• Disease
  syndrome

Gene info

• Identity
  HGNC:8574
• Gene
  PAFAH1B1
• Long gene name
  platelet activating factor acetylhydrolase 1b regulatory subunit 1
• Synonyms gene
  • MDCR
  • MDS
• Synonyms gene name
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
  • Miller-Dieker syndrome chromosome region
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
  • platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
  • platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
• Synonyms
  • LIS1
  • PAFAH
  • NudF
• Synonyms name
  • lissencephaly-1
• GenBank acession
  • L25107
• Locus
  17p13.3
• Discovery year
  1998-04-03
• Entrez gene record
  5048
• Pubmed identfication
  • 8355785
  • 9063735
• RefSeq identity
  • NM_000430
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000177574

Gene info

• Identity
  HGNC:9040
• Gene
  PLA2G7
• Long gene name
  phospholipase A2 group VII
• Synonyms gene name
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
• Synonyms
  • PAFAH
  • LDL-PLA2
• GenBank acession
  • U20157
• Locus
  6p12.3
• Discovery year
  1999-09-20
• Entrez gene record
  7941
• Pubmed identfication
  • 7700381
  • 8624782
• Classification
  • Phospholipases
• VEGA ID
  OTTHUMG00000014789

Gene info

• Identity
  HGNC:9717
• Gene
  PEX2
• Long gene name
  peroxisomal biogenesis factor 2
• Synonyms gene
  • PXMP3
• Synonyms gene name
  • peroxisomal membrane protein 3 (35kD, Zellweger syndrome)
  • peroxisomal membrane protein 3, 35kDa
• Synonyms
  • PMP35
  • PAF-1
  • RNF72
  • ZWS3
• Synonyms name
  • Zellweger syndrome
  • peroxin 2
• GenBank acession
  • M86852
• Locus
  8q21.13
• Discovery year
  1992-03-03
• Entrez gene record
  5828
• Pubmed identfication
  • 1546315
  • 8858157
• RefSeq identity
  • NM_000318
• Classification
  • Peroxins
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000164530
• Locus Specific Databases
  • dbPEX, PEX Gene Database

Gene info

• Identity
  HGNC:28961
• Gene
  PCLAF
• Long gene name
  PCNA clamp associated factor
• Synonyms gene
  • KIAA0101
• Synonyms gene name
  • KIAA0101
• Synonyms
  • NS5ATP9
  • OEATC-1
  • p15(PAF)
  • PAF15
• Synonyms name
  • PCNA-associated factor
• GenBank acession
  • D14657
• Locus
  15q22.31
• Discovery year
  2004-06-24
• Entrez gene record
  9768
• Pubmed identfication
  • 11313979
  • 16288740
• RefSeq identity
  • NM_014736
• VEGA ID
  OTTHUMG00000133017

Gene info

• Identity
  HGNC:8859
• Gene
  PEX6
• Long gene name
  peroxisomal biogenesis factor 6
• Synonyms
  • PXAAA1
  • PAF-2
• GenBank acession
  • U56602
• Locus
  6p21.1
• Discovery year
  1997-05-22
• Entrez gene record
  5190
• Pubmed identfication
  • 8670792
• RefSeq identity
  • NM_000287
• Classification
  • Peroxins
  • AAA ATPases
• VEGA ID
  OTTHUMG00000014713
• Locus Specific Databases
  • dbPEX, PEX Gene Database

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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