Carubicin (Free base)

  • Catalog number
    B1853-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    (8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,6,8,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Carminomycin I
  • Description
    Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Also acts as an inducer of apoptosis that targets Golgi complex in clear cell renal carcinoma cells.
  • CAS Number
    50935-04-1
  • Structure Available
    Yes
  • Molecular Formula
    C₂₆H₂₇NO₁₀
  • Molecular Weight
    513.49
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    An anthracycline antineoplastic antibiotic
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    443831
  • SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5O)O)(C(=O)C)O)N)O
  • InChi
    InChI=1S/C26H27NO10/c1-9-21(30)13(27)6-16(36-9)37-15-8-26(35,10(2)28)7-12-18(15)25(34)20-19(23(12)32)22(31)11-4-3-5-14(29)17(11)24(20)33/h3-5,9,13,15-16,21,29-30,32,34-35H,6-8,27H2,1-2H3/t9-,13-,15-,16-,21+,26-/m0/s1
  • InChi Key
    XREUEWVEMYWFFA-CSKJXFQVSA-N
  • MSDS Available
    Yes
  • Gene target
    Carubicin   Free   base  
  • Short name
    Carubicin (Free base)
  • Alternative name
    Carubicin (Free base)
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