LIMKi 3 for cell activation

LIMKi 3 for cell activation is available 2 times from Biovision labs

B1095-25 | LIMKi 3 for cell activationsize: 25 mg | 684.61 USD

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B1095-5 | LIMKi 3 for cell activationsize: 5 mg | 216.56 USD

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  • Description
    LIMKi 3 is a potent, and cell-permeable inhibitor of LIMK1 (IC₅₀ = 7 nM) and LIMK2 (IC₅₀ = 8 nM) and inhibits coflin phosphorylation in MDA-MB-231 breast cancer cells without affecting tubulin polymerization or inducing cytotoxicity. It also reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
  • Peptide sequence
    N/A
  • CAS number
    1338247-35-0
  • Molecular weight
    431.29
  • Category
    Biochemicals
  • Other name
    N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide ; BMS 5
  • Molecular formula
    C₁₇H₁₄Cl₂F₂N₄OS
  • Physical appearance
    White Solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>40mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    LIMKi 3 for activation
  • Technique
    activation
  • Alternative name
    LIMKi 3 to measure cellular activation
  • Tissue
    cell
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