LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647

• Catalog number
  bs-3247R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-LIMK1 Thr508/LIMK2 Thr505 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LIMK1 Thr508/LIMK2 Thr505
• Specificity
  This is a highly specific antibody against LIMK1 Thr508/LIMK2 Thr505.
• Modification
  Phosphorylation
• Modification Site
  Thr505
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
• Gene ID Number
  3984
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  LIMK1Thr508; EC 2.7.11.1; LIM domain kinase 1; LIM mot-containing protein kinase; LIMK; LIMK-1; LIMK2; LIMK-2; LIM domain kinase 2; LIMK1_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-LIMK1 Thr508/LIMK2 Thr505 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  LIMK1   Thr508   LIMK2   Thr505  
• Gene symbol
  LIMK2, LIMK1
• Short name
  Anti-LIMK1 Thr508/LIMK2 Thr505
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6614
• Gene
  LIMK2
• Long gene name
  LIM domain kinase 2
• GenBank acession
  • D45906
• Locus
  22q12.2
• Discovery year
  1997-08-28
• Entrez gene record
  3985
• Pubmed identfication
  • 8537403
  • 10591208
• RefSeq identity
  • NM_016733
• Classification
  • PDZ domain containing
  • LIMK/TESK kinase family
  • LIM domain containing
• VEGA ID
  OTTHUMG00000151251

Gene info

• Identity
  HGNC:6613
• Gene
  LIMK1
• Long gene name
  LIM domain kinase 1
• Synonyms
  • LIMK
• GenBank acession
  • D26309
• Locus
  7q11.23
• Discovery year
  1996-03-14
• Entrez gene record
  3984
• Pubmed identfication
  • 8673124
  • 8812460
• RefSeq identity
  • NM_002314
• Classification
  • LIM domain containing
  • PDZ domain containing
  • LIMK/TESK kinase family
• VEGA ID
  OTTHUMG00000023448

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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