LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647
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Catalog number
bs-3247R-A647
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Price
Please ask
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Size
100ul
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Long name
LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647 Conjugated
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Also known as
Anti-LIMK1 Thr508/LIMK2 Thr505 PAb ALEXA FLUOR 647
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 647
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
LIMK1 Thr508/LIMK2 Thr505
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Specificity
This is a highly specific antibody against LIMK1 Thr508/LIMK2 Thr505.
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Modification
Phosphorylation
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Modification Site
Thr505
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505
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Gene ID Number
3984
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development; it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
650nm/665nm
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Synonyms
LIMK1Thr508; EC 2.7.11.1; LIM domain kinase 1; LIM mot-containing protein kinase; LIMK; LIMK-1; LIMK2; LIMK-2; LIM domain kinase 2; LIMK1_HUMAN.
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-LIMK1 Thr508/LIMK2 Thr505 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 647
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French translation
anticorps
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Gene target
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Gene symbol
LIMK2, LIMK1
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Short name
Anti-LIMK1 Thr508/LIMK2 Thr505
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 647
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Alternative name
LIMK1(Thr508)/LIMK2(Thr505) Antibody, ALEXA FLUOR 647
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
LIM domain kinase 2
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GenBank acession
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Locus
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Discovery year
1997-08-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- LIMK/TESK kinase family
- LIM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
LIM domain kinase 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-03-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- LIM domain containing
- PDZ domain containing
- LIMK/TESK kinase family
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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