LIM kinase 1 2 Antibody Conjugated
LIM kinase 1 2 Antibody Conjugated is available 7 times from Bioss primary conjugated antibodies labs
- CategoryConjugated Primary Antibodies
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenLIM kinase 1 + 2
- SpecificityThis is a highly specific antibody against LIM kinase 1 + 2.
- Modification siteNone
- ClonePolyclonal antibody
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human LIM kinase 1 + 2
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundLIMK 1 and 2 likely regulate aspects of the cytoskeleton, through control of the organization of actin filaments. They can phosphorylate an actin-binding protein, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament.The phosphorylation of cofilin via LIMK inactivates this potential. LIMK1 is highly active in the brain and spinal chord, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues. LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition). These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, drawing, constructing models, and assembling puzzles. LIMK1 is specifically stimulated by Rac, one of the Rho family proteins, while LIMK2 activity is activated under the control of other Rho family members, Rho and Cdc42, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics.
- Purification methodThis antibody was purified via Protein A.
- SynonymsLIM kinase 1+2; LIMK1+LIMK2; LIM domain kinase 1; LIM domain kinase 2; LIMK1; LIMK2;LIMK1_HUMAN; LIMK2_HUMAN.
- Gene target
- Alternative techniqueantibodies
bs-11871R-Biotin | LIM kinase 1 + 2 Antibody, Biotin Conjugatedsize: 0.1ml | 408.79 USD
bs-11871R-Cy3 | LIM kinase 1 + 2 Antibody, Cy3 Conjugatedsize: 0.1ml | 429.66 USD
bs-11871R-Cy5 | LIM kinase 1 + 2 Antibody, Cy5 Conjugatedsize: 0.1ml | 429.66 USD
- Catalog numberbs-11871R-Cy5
- Price429.66 USD
- Long nameLIM kinase 1 + 2 Polyclonal Antibody, Cy5 Conjugated
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission625,650nm/670nm
- PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
- Additional conjugationCy5.5
- French translationanticorps
- Short nameLIM kinase 1 + 2 Antibody, Conjugated
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative nameLIM phosphorylation catalyst 1 and 2 (Antibody to), cyanine 5 coupled
1. Gene info
- Long gene namePDZ and LIM domain 5
- GenBank acession
- Discovery year2005-01-12
- Entrez gene record
- Pubmed identfication
- LIM domain containing
- PDZ domain containing
- Havana BLAST/BLAT
- ConceptScope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- Entrez Gene
bs-11871R-Cy5.5 | LIM kinase 1 + 2 Antibody, Cy5.5 Conjugatedsize: 0.1ml | 429.66 USD
bs-11871R-Cy7 | LIM kinase 1 + 2 Antibody, Cy7 Conjugatedsize: 0.1ml | 429.66 USD
bs-11871R-FITC | LIM kinase 1 + 2 Antibody, FITC Conjugatedsize: 0.1ml | 408.79 USD
bs-11871R-HRP | LIM kinase 1 + 2 Antibody, HRP Conjugatedsize: 0.1ml | 429.66 USD
Supplier:Bioss Polyclonal Antibodies