LGR6 Antibody, Cy3 Conjugated

• Catalog number
  bs-8609R-Cy3
• Price
  Please ask
• Size
  0.1ml

• Long name
  LGR6 Polyclonal Antibody, Cy3 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy3
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LGR6
• Specificity
  This is a highly specific antibody against LGR6.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  430-480/967
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human LGR6
• Gene ID number
  59352
• Swiss Prot
  Q9HBX8
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  512,550nm/570,615nm
• Synonyms
  GPCR; VTS20631; Leucine-rich repeat-containing G-protein coupled receptor 6; LGR6; UNQ6427/PRO213
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-LGR6 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
• Additional conjugation
  cy3 conjugation kit
• French translation
  anticorps

• Gene target
  LGR6   Conjugated  
• Gene symbol
  LGR6
• Short name
  Anti-LGR6
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy3
• Alternative name
  Anti-LGR6 PAb Cy3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19719
• Gene
  LGR6
• Long gene name
  leucine rich repeat containing G protein-coupled receptor 6
• Synonyms
  • FLJ14471
• GenBank acession
  • AF190501
• Locus
  1q32.1
• Discovery year
  2003-12-04
• Entrez gene record
  59352
• Pubmed identfication
  • 10935549
• RefSeq identity
  • NM_021636
• Classification
  • G protein-coupled receptors, Class A orphans
• VEGA ID
  OTTHUMG00000041383

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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