LGI4 Antibody

• Catalog number
  bs-8303R
• Price
  Please ask
• Size
  0.1ml

• Long name
  LGI4 Primary Polyclonal Antibody
• Also known as
  LGI4 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LGI4
• Specificity
  This is a highly specific antibody against LGI4.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LGI4
• Gene ID number
  163175
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Leucine rich glioma inactivated gene 4; Leucine rich glioma inactivated protein 4; leucine-rich repeat LGI family member 4; Leucine rich repeat LGI family member 4; LGI1 like protein 3; LGI4; Lgi4 protein; Lgil3; LGI4_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LGI4  
• Gene symbol
  LGI4
• Short name
  Anti-LGI4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  LGI4 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18712
• Gene
  LGI4
• Long gene name
  leucine rich repeat LGI family member 4
• Synonyms gene name
  • leucine-rich repeat LGI family, member 4
• GenBank acession
  • AJ487519
• Locus
  19q13.12
• Discovery year
  2002-05-30
• Entrez gene record
  163175
• Pubmed identfication
  • 12023020
• Classification
  • LGI family
• VEGA ID
  OTTHUMG00000044558

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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