LGALS8, human recombinant
-
Catalog number
7367-50
-
Price
Please ask
-
Size
50 ug
-
-
Synonyms
Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1
-
Alternative_names
Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1
-
Description
A specific identifier of malignant tissues.
-
Recombinant
Yes
-
Source
E. coli
-
Purity by SDS PAGE
≥90%
-
Assay
SDS-PAGE
-
Molecular Weight
37.9 kDa (337 aa, 1-317 aa + His Tag).
-
Storage Temp
-80°C
-
Shipping
Dry Ice
-
Shelf Life
12 months
-
Concentration
0.5 mg/ml
-
Appearance
Liquid
-
Physical form description
0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 M NaCl and 10% glycerol.
-
Background Information
LGALS8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. Recombinant human LGALS8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
-
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN AKSFNVDLLA GKSKDIALHL NPRLNIKAFV RNSFLQESWG EEERNITSFP FSPGMYFEMI IYCDVREFKV AVNGVHSLEY KHRFKELSSI DTLEINGDIH LLEVRSW
-
Handling
Centrifuge the vial prior to opening.
-
Usage
For Research Use Only! Not to be used in humans
-
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
LGALS8-AS1, LGALS8
-
Short name
LGALS8, recombinant
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Species
Human, Humans
-
Alternative name
LGALS8, H. sapiens Rec.
-
Alternative technique
rec
-
Gene info
-
Identity
-
Gene
-
Long gene name
LGALS8 antisense RNA 1
-
Synonyms gene name
- LGALS8 antisense RNA 1 (non-protein coding)
-
Locus
-
Discovery year
2011-08-04
-
Entrez gene record
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
galectin 8
-
Synonyms gene name
- lectin, galactoside-binding, soluble, 8
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1995-05-25
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products