-
Products_type
Antibody
-
Products_short_name
[Blood Group Antigen Lewis B]
-
Products_name_syn
[Blood group Lewis alpha-4-fucosyltransferase; Fucosyltransferase 3; Fucosyltransferase III; FucT-III; FUT3; Galactoside 3(4)-L-fucosyltransferase; gastric mucin; leB; lewis antigen system; lewis B blood group antigen; Lewis FT; major airway glycoprotein]
-
Other_names
[galactoside 3(4)-L-fucosyltransferase; Galactoside 3(4)-L-fucosyltransferase; galactoside 3(4)-L-fucosyltransferase; fucosyltransferase 3 (Lewis blood group); Blood group Lewis alpha-4-fucosyltransferase; Lewis FT; Fucosyltransferase 3; Fucosyltransferase III; FucT-III]
-
Products_gene_name
[FUT3]
-
Other_gene_names
[FUT3; FUT3; LE; Les; FT3B; CD174; FucT-III; FT3B; LE; Lewis FT; FucT-III]
-
Clonality
Monoclonal
-
Clone
[2-25LE; same as LWB01]
-
Reactivity
Human, Guinea Pig
-
Specificity
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.
-
Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
-
Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Tested_application
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
-
Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Description
Antigens are peptides or recombinant or native dependent on the production method. Blood is slightly basic and contains proteins, hemoglobin, albumins in its serum. MyBioSource supplies this blood related product in 1.
-
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus
-
French translation
anticorps
-
Gene target
-
Short name
Blood Group Antigen Lewis B Mouse Monoclonal Antibody
-
Technique
Mouse monoclonal, Antibody, antigen, blood, Mouse, antibodies against human proteins, antibodies for, antigenes, blood samples, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
-
Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
-
Isotype
IgG1, kappa
-
Species
Mouse, Mouses
-
Alternative name
Blood family protein Lewis B Mouse monoclonal (antibody to-)
-
Alternative technique
antibodies, antigenes, sera, murine
-
Tissue
blood
-
