Lenvatinib for cell activation

Lenvatinib for cell activation is available 2 times from Biovision labs

B1157-5 | Lenvatinib for cell activationsize: 5 mg | 166.98 USD

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B1157-25 | Lenvatinib for cell activationsize: 25 mg | 486.82 USD

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  • Description
    Lenvatinib is a potent inhibitor of multiple receptor tyrosine kinases, with IC₅₀ values of  22 nM, 4 nM, 5.2 nM, 39 nM and 35 nM on VEGFR-1, VEGFR-2, VEGFR-3, PDGFRβ and RET, respectively. It inhibits SCF- and VEGF-induced angiogenesis of human umbilical vein endothelial cells that express the SCF receptor KIT, with IC₅₀ values of 5.2 nM and 5.1 nM, respectively. Lenvatinib inhibits tumor growth in the human small cell lung cancer H146 xenograft model.
  • Peptide sequence
    N/A
  • CAS number
    417716-92-8
  • Molecular weight
    426.85
  • Category
    Biochemicals
  • Other name
    4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide; E7080
  • Molecular formula
    C₂₁H₁₉ClN₄O₄
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>35 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Lenvatinib for activation
  • Technique
    activation
  • Alternative name
    Lenvatinib to measure cellular activation
  • Tissue
    cell
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