LDLR (Low-density Lipoprotein Receptor, LDL Receptor) (PE) Antibody

• Catalog number
  GEN609177
• Price
  Please ask
• Size
  100 Tests

• Also known as
  LDLR
• Other names
  low-density lipoprotein receptor isoform 1; Low-density lipoprotein receptor; low-density lipoprotein receptor; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; low density lipoprotein receptor; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  LDLR; LDLR; FH; FHC; LDLCQ2; LDL receptor
• Gene name synonims
  LDLR; LDLR; FH; FHC; LDLCQ2; LDL receptor
• Other gene names
  LDLR; LDLR; FH; FHC; LDLCQ2; LDL receptor
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  11C32
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human LDLR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
• Concentration
  N/A
• Storage and shipping
  May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Stable for 12 months at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  High and low density proteins are supplied by MBS Monoclonals in volumes of 1. Other densities are possible. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  LDLR   Lipoprotein   Receptor   LDL   Receptor  
• Gene symbol
  LDLR, LDLR-AS1, PLA2G7
• Short name
  LDLR ( - Lipoprotein Receptor, LDL Receptor) (PE) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Label
  PE
• Alternative name
  Anti-LDLR (Low-density Lipoprotein Receptor, LDL Receptor) (PE)
• Alternative technique
  antibodies
• Alternative to gene target
  low density lipoprotein receptor, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, very-low-density lipoprotein particle receptor activity, Cell surfaces, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276

Gene info

• Identity
  HGNC:6547
• Gene
  LDLR
• Long gene name
  low density lipoprotein receptor
• Synonyms
  • LDLCQ2
• Synonyms name
  • familial hypercholesterolemia
• GenBank acession
  • AY114155
• Locus
  19p13.2
• Discovery year
  1986-01-01
• Entrez gene record
  3949
• Classification
  • Low density lipoprotein receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000171935
• Locus Specific Databases
  • UCL LDLR-LOVD, British Heart Foundation variant database
  • UMD Locus Specific Databases
  • LRG_274

Gene info

• Identity
  HGNC:54407
• Gene
  LDLR-AS1
• Long gene name
  LDLR antisense RNA 1
• Synonyms
  • BM450697
• Locus
  19p13.2
• Discovery year
  2019-08-08
• Entrez gene record
  115271120
• Pubmed identfication
  • 31279228
• RefSeq identity
  • NR_163945
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:9040
• Gene
  PLA2G7
• Long gene name
  phospholipase A2 group VII
• Synonyms gene name
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
• Synonyms
  • PAFAH
  • LDL-PLA2
• GenBank acession
  • U20157
• Locus
  6p12.3
• Discovery year
  1999-09-20
• Entrez gene record
  7941
• Pubmed identfication
  • 7700381
  • 8624782
• Classification
  • Phospholipases
• VEGA ID
  OTTHUMG00000014789

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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