LASS2 (Longevity Assurance Homolog 2) - Blocking Peptide

  • Catalog number
    X2288B
  • Price
    Please ask
  • Size
    50 μg
  • Category
    Proteins & Peptides
  • Long description
    LASS2, a human homologue of the yeast longevity assurance gene LAG1 is highly expressed in liver and kidney as compared to the expression of the human LAG1 homologue LAG1Hs-1. LASS2 is located on chromosome 1q11. The LASS2 protein interacts with several membrane-associated receptors or transporters. LASS2 protein inhibits the colony formation of human hepatoma cells in vitro, which suggests that this gene may be involved in the regulation of cell growth.
  • Antibody come from
    Synthetic peptide derived from human Lass2 protein
  • Other description
    Provided as solution in phosphate buffered saline with 0.08% sodium azide.
  • Clone
    not specified
  • Antigen antibody binding interaction
    LASS2 (Longevity Assurance Homolog 2) - Blocking Peptide
  • Antibody is raised in
    see techfile
  • Antibody s reacts with
    Human, Rat, Mouse
  • Antibody s reacts with these species
    This antibody doesn't cross react with other species
  • Antibody s specificity
    No Data Available
  • Application
    Western Blot
  • Antibody s suited for
    Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Storage
    -20ºC
  • Relevant references
    1: Becker I, Wang-Eckhardt L, Yaghootfam A, Gieselmann V, Eckhardt M.Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2._x000B_Histochem Cell Biol. 2008 Feb;129(2):233-41. Epub 2007 Sep 28._x000B__x000B_2: Wang X, CarrŽ W, Saxton AM, Cogburn LA. Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken._x000B_Cytogenet Genome Res. 2007;117(1-4):174-88._x000B__x000B_3:Senkal CE, Ponnusamy S, Rossi MJ, Bialewski J, Sinha D, Jiang JC, Jazwinski SM, Hannun YA, Ogretmen B. Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas._x000B_Mol Cancer Ther. 2007 Feb;6(2):712-22._x000B__x000B_4: Yu Y, Lu H, Pan H, Ma JH, Ding ZJ, Li YY. Expression of LASS2 controlled by LAG1 or ADH1 promoters cannot functionally complement Lag1p._x000B_Microbiol Res. 2006;161(3):203-11. Epub 2005 Sep 22._x000B_
  • Protein number
    see ncbi
  • Warnings
    This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
  • Test
    You can block the antibody by the specific target amino acid sequence of peptide.
  • Properties
    blocking peptide
  • Description
    Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
  • Gene target
  • Gene symbol
    CERS2
  • Short name
    LASS2 (Longevity Assurance Homolog 2) - Blocking Peptide
  • Technique
    blocking peptide, Blocking, peptide, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
  • Isotype
    not specified
  • Label
    unlabeled
  • Alternative name
    LASS2 (Longevity Assurance Homolog 2) - inhibiting short protein sequence
  • Alternative technique
    control, peptides
Gene info
  • Identity
  • Gene
  • Long gene name
    ceramide synthase 2
  • Synonyms gene
  • Synonyms gene name
    • longevity assurance (LAG1, S. cerevisiae) homolog 2
    • LAG1 longevity assurance homolog 2 (S. cerevisiae)
    • LAG1 homolog, ceramide synthase 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-09-10
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • CERS class homeoboxes
  • VEGA ID
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