Langerin/CD207 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-2650R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Langerin/CD207 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Langerin/CD207
• Specificity
  This is a highly specific antibody against Langerin/CD207.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  213-223/328
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD207
• Gene ID Number
  50489
• Swiss Prot
  Q9UJ71
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Langerin/CD207 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  Langerin/CD207  
• Gene symbol
  CD207
• Short name
  Anti-Langerin/CD207
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  CD207 molecule, langerin, CD207 and IDBG-55659 and ENSG00000116031 and 50489, carbohydrate binding, Plasma membranes, Cd207 and IDBG-161509 and ENSMUSG00000034783 and 246278, CD207 and IDBG-631820 and ENSBTAG00000004562 and 511000

Gene info

• Identity
  HGNC:17935
• Gene
  CD207
• Long gene name
  CD207 molecule
• Synonyms gene name
  • CD207 antigen, langerin
  • CD207 molecule, langerin
• Synonyms
  • Langerin
  • CLEC4K
• GenBank acession
  • AJ242859
• Locus
  2p13.3
• Discovery year
  2003-10-02
• Entrez gene record
  50489
• Pubmed identfication
  • 10661407
  • 9847074
• RefSeq identity
  • NM_015717
• Classification
  • Scavenger receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000153176

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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