EZH1 Antibody, Biotin Conjugated

• Catalog number
  bs-6528R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  EZH1 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EZH1
• Specificity
  This is a highly specific antibody against EZH1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic peptide derived from human EZH1
• Gene ID number
  2145
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Enhancer of zeste homolog 1Drosophila; Enhancer of zeste homolog 1; ENX-2; ENX2; EZH1; EZH1: enhancer of zeste homolog 1 Drosophila; EZH1_HUMAN; Histone-lysine N-methyltransferase EZH1; KIAA0388.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  EZH1   Conjugated  
• Gene symbol
  EZH1, EZH2
• Short name
  Anti-EZH1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-EZH1 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3526
• Gene
  EZH1
• Long gene name
  enhancer of zeste 1 polycomb repressive complex 2 subunit
• Synonyms gene name
  • enhancer of zeste (Drosophila) homolog 1
  • enhancer of zeste homolog 1 (Drosophila)
• Synonyms
  • KIAA0388
  • KMT6B
• Locus
  17q21.2
• Discovery year
  1995-12-21
• Entrez gene record
  2145
• Pubmed identfication
  • 8921387
• RefSeq identity
  • NM_001991
• Classification
  • SET domain containing
  • Polycomb repressive complex 2
  • Lysine methyltransferases
  • Myb/SANT domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000180645

Gene info

• Identity
  HGNC:3527
• Gene
  EZH2
• Long gene name
  enhancer of zeste 2 polycomb repressive complex 2 subunit
• Synonyms gene name
  • enhancer of zeste (Drosophila) homolog 2
  • enhancer of zeste homolog 2 (Drosophila)
• Synonyms
  • EZH1
  • ENX-1
  • KMT6
  • KMT6A
• Locus
  7q36.1
• Discovery year
  1995-12-21
• Entrez gene record
  2146
• Pubmed identfication
  • 8954776
  • 17172412
• RefSeq identity
  • NM_004456
• Classification
  • SET domain containing
  • Polycomb repressive complex 2
  • Lysine methyltransferases
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000158973
• Locus Specific Databases
  • LRG_531

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products