Kisspeptin Antibody

• Catalog number
  bs-0749R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Kisspeptin Primary Polyclonal Antibody
• Also known as
  Kisspeptin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Kisspeptin
• Specificity
  This is a highly specific antibody against Kisspeptin. This antibody detects Kisspeptin-10 region of Kisspeptin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  112-121/138
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Kiss-1
• Gene ID number
  3814
• Swiss Prot
  Q15726
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-1 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-1, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-1 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HH13; KiSS-1; Metastasis-suppressor KiSS-1; Kisspeptin-1; KISS1; PP598
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kisspeptin  
• Gene symbol
  KISS1
• Short name
  Anti-Kisspeptin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Kisspeptin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6341
• Gene
  KISS1
• Long gene name
  KiSS-1 metastasis suppressor
• Synonyms name
  • prepro-kisspeptin
  • kisspeptin
• GenBank acession
  • U43527
• Locus
  1q32.1
• Discovery year
  1998-05-18
• Entrez gene record
  3814
• Pubmed identfication
  • 9192814
  • 9806840
• RefSeq identity
  • NM_002256
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000036060

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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