KALRN/Duo Antibody, ALEXA FLUOR 350

• Catalog number
  bs-11861R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  KALRN/Duo Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-KALRN/Duo PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KALRN/Duo
• Specificity
  This is a highly specific antibody against KALRN/Duo.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KALRN/Duo
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  Duo; FLJ16443; HAPIP; Huntingtin associated protein interacting protein duo ; Huntingtin-associated protein-interacting protein; Kalirin isoform 2; Kalirin; KALRN ; KALRN_HUMAN ; Protein Duo; RhoGEF kinase; Serine/threonine kinase with Dbl and pleckstrin homology domains ; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  KALRN/Duo  
• Gene symbol
  KALRN
• Short name
  Anti-KALRN/Duo
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  KALRN/Duo Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies
• Alternative to gene target
  kalirin, RhoGEF kinase, ARHGEF24 and CHD5 and CHDS5 and DUET and DUO and HAPIP and TRAD, KALRN and IDBG-53661 and ENSG00000160145 and 8997, transferase activity, Cytoplasm, Kalrn and IDBG-155984 and ENSMUSG00000061751 and 545156, KALRN and IDBG-633466 and ENSBTAG00000002640 and 540675

Gene info

• Identity
  HGNC:4814
• Gene
  KALRN
• Long gene name
  kalirin RhoGEF kinase
• Synonyms gene
  • HAPIP
• Synonyms gene name
  • huntingtin-associated protein interacting protein (duo)
• Synonyms
  • duo
  • Hs.8004
  • TRAD
  • DUET
  • Kalirin
  • ARHGEF24
• Synonyms name
  • serine/threonine kinase with Dbl and pleckstrin homology domains
• GenBank acession
  • U94190
• Locus
  3q21.1-q21.2
• Discovery year
  1999-01-13
• Entrez gene record
  8997
• Pubmed identfication
  • 9285789
  • 10023074
• RefSeq identity
  • NM_003947
• Classification
  • I-set domain containing
  • Fibronectin type III domain containing
  • Dbl family Rho GEFs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000125545

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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