MAPK8/9 Antibody
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Catalog numberPA1407
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PricePlease ask
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Size0,1 mg
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Target antigenMAPK8/9
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman
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AnalysesWB,IHC-P,ICC
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ImmunogenA synthetic peptide corresponding to a sequence in the middle region of human MAPK8/9(344-363aa EREHTIEEWKELIYKEVMDL), identical to the related mouse and rat sequences.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the MAPK8/9 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe MAPK8/9 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundMitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase family. The International Radiation Hybrid Mapping Consortium mapped the MAPK8 gene to chromosome 10. The single long open reading frame encodes a putative protein kinase with a predicted mass of 44.2 kD. This kinase play a key role in T cell proliferation, apoptosis and differentiation.
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Related articles1. Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ (Apr 1994). "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain". Cell 76 (6): 1025–37. doi:10.1016/0092-8674(94)90380-8. PMID 8137421. 2. Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, Davis RJ (Jul 1996). "Selective interaction of JNK protein kinase isoforms with transcription factors". EMBO J 15 (11): 2760–70. PMC 450211. PMID 8654373.
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Gene NameMAPK8
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Protein NameMitogen-activated protein kinase 8(MAP kinase 8/MAPK 8)
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Gene Full NameMitogen-activated Protein Kinase 8
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SynonymsJNK-46 antibody|Stress-activated protein kinase 1c antibody
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Uniprot IDP45983
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMAPK8
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Short nameMAPK8/9 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative namemitogen-activated protein kinase 8/9 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetmitogen-activated protein kinase 8, JNK and JNK-46 and JNK1 and JNK1A2 and JNK21B1/2 and PRKM8 and SAPK1 and SAPK1c, MAPK8 and IDBG-73479 and ENSG00000107643 and 5599, transferase activity, nuclei, Mapk8 and IDBG-148417 and ENSMUSG00000021936 and 26419, MAPK8 and IDBG-631635 and ENSBTAG00000007876 and 539941
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Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase 8
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-28
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Entrez gene record
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Pubmed identfication
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Classification
- Mitogen-activated protein kinases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data