JNJ 26854165 for cell activation

JNJ 26854165 for cell activation is available 2 times from Biovision labs

2479-25 | JNJ-26854165 for cell activationsize: 25 mg | 432.96 USD

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2479-5 | JNJ-26854165 for cell activationsize: 5 mg | 154.04 USD

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  • Description
    A novel p53-activating tryptamine derivative that acts as a HDM2 (Human Double Minute-2) antagonist with potential antineoplastic activity. JNJ-26854165 inhibits the binding of the HDM2–p53 complex to the proteasome, blocking the degradation of p53. It displays potent anti-proliferative and apoptosis-inducing activity in a broad range of p53 wild type and mutant tumor models.
  • Peptide sequence
    N/A
  • CAS number
    881202-45-5
  • Molecular weight
    328.41
  • Category
    Biochemicals
  • Other name
    1-N-[2-(1H-indol-3-yl)ethyl]-4-N-pyridin-4-ylbenzene-1,4-diamine; Serdemetan
  • Molecular formula
    C₂₁H₂₀N₄
  • Physical appearance
    Off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    N/A
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>50 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    JNJ-26854165 for activation
  • Technique
    activation
  • Alternative name
    JNJ-26854165 to measure cellular activation
  • Tissue
    cell
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