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JIP2 Antibody, Cy7 Conjugated

JIP2 Antibody, Cy7 Conjugated is available 1 time from Bioss primary conjugated antibodies labs

bs-13647R-Cy7 | JIP2 Antibody, Cy7 Conjugated size: 0.1ml | 397.99 USD

Properties If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugated These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
Additional conjugation Cy7
French translation anticorps
1. Gene info
Identity 6883
Gene MAPK8IP2
Long gene name mitogen-activated protein kinase 8 interacting protein 2
Synonyms gene
  • PRKM8IPL
Synonyms gene name
  • PRKM8 interacting protein-like
Synonyms
  • IB2
  • JIP2
Synonyms name
  • islet-brain 2
  • JNK-interacting protein 2
GenBank acession
  • AL021708
Locus 22q13.33
Discovery year 1999-10-12
Entrez gene record 23542
Pubmed identfication
  • 10490659
RefSeq identity
  • NM_012324
Havana BLAST/BLAT OTTHUMG00000150181
MeSH Data
Name Blotting, Western
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Long name JIP2 Polyclonal Antibody, Cy7 Conjugated
Category Conjugated Primary Antibodies
Conjugation Cy7
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen JIP2
Specificity This is a highly specific antibody against JIP2.
Modification Unmodified
Modification site None
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source KLH conjugated synthetic peptide derived from human JIP2
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Crossreactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1). JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser-63 and Ser-73, resulting in transcriptional activation (2-5). Two additional JNK family members have been identified as JNK2 and JNK3 (3). JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6). Multiple splice variants if JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain (7).
Purification method This antibody was purified via Protein A.
Storage conditions Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission 743nm/767nm
Synonyms MAPK8IP2; C jun amino terminal kinase interacting protein 2; C-jun-amino-terminal kinase-interacting protein 2; Homologous to mouse JIP 1; IB 2; IB-2; IB2; Islet brain 2; Islet-brain-2; JIP 2; JIP-2; JIP2; JIP2_HUMAN; JNK interacting protein 2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; MAPK8IP2; Mitogen activated protein kinase 8 interacting protein 2; Mitogen-activated protein kinase 8-interacting protein 2; PRKM8 interacting protein like; PRKM8IPL.
Gene targetJIP2 Conjugated
Short name JIP2 Antibody, Conjugated
Technique Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
Label Cy7
Alternative name JIP2 (Antibody to), cyanine 7 coupled
Alternative technique antibodies
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