Jervine for cell activation

Jervine for cell activation is available 2 times from Biovision labs

2357-5 | Jervine for cell activationsize: 5 mg | 678.49 USD

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2357-1 | Jervine for cell activationsize: 1 mg | 218.72 USD

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  • Description
    Cell-permeable. Structurally similar to cyclopamine (Cat. No. 1578). Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Tomatidine (Cat. No. 1893) is a useful negative control.
  • Peptide sequence
    N/A
  • CAS number
    469-59-0
  • Molecular weight
    425.6
  • Category
    Biochemicals
  • Other name
    (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,1­1bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexad­ecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H­-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1­H)-one
  • Molecular formula
    C₂₇H₃₉NO₃
  • Physical appearance
    White to off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by TLC
  • Reconstitute instructions
    DMSO (5 mg/ml) or EtOH (10 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Jervine for activation
  • Technique
    activation
  • Alternative name
    Jervine to measure cellular activation
  • Tissue
    cell
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