Jarid1C Antibody, ALEXA FLUOR 350

• Catalog number
  bs-8178R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  Jarid1C Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-Jarid1C PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Jarid1C
• Specificity
  This is a highly specific antibody against Jarid1C.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid1C/KDM5C
• Gene ID Number
  11184
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.Tissue specificity:br>Involvement in disease:Defects in KDM5C are the cause of mental retardation syndromic X-linked JARID1C-related (MRXSJ) . MRXSJ is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRXSJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, seizures, facial dysmorphism.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  SmcX protein; Xe169 protein; DXS1272E; Histone demethylase JARID1C; JmjC domain containing protein SMCX; Jumonji AT rich interactive domain 1C; Jumonji/ARID domain-containing protein 1C; KDM5C; KDM5C_HUMAN; Lysine K specic demethylase 5C; Lysine-specic demethylase 5C; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; rbp2 like protein; Selected cDNA on X; Smcx homolog X chromosome; SmcX protein; Smcy homolog X linked; XE169; Xe169 protein.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  Jarid1C  
• Gene symbol
  KDM5C
• Short name
  Anti-Jarid1C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  Jarid1C Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11114
• Gene
  KDM5C
• Long gene name
  lysine demethylase 5C
• Synonyms gene
  • SMCX
  • JARID1C
  • MRX13
• Synonyms gene name
  • Jumonji, AT rich interactive domain 1C (RBP2-like)
  • Smcy homolog, X-linked (mouse)
  • jumonji, AT rich interactive domain 1C
  • mental retardation, X-linked 13
  • lysine (K)-specific demethylase 5C
• Synonyms
  • DXS1272E
  • XE169
• GenBank acession
  • Z29650
• Locus
  Xp11.22
• Discovery year
  1999-04-23
• Entrez gene record
  8242
• Pubmed identfication
  • 7951230
  • 8162017
  • 19826449
• RefSeq identity
  • NM_004187
• Classification
  • MicroRNA protein coding host genes
  • PHD finger proteins
  • Lysine demethylases
  • AT-rich interaction domain containing
• VEGA ID
  OTTHUMG00000021606
• Locus Specific Databases
  • KDM5C database at LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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