Ivabradine Hydrochloride
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Catalog numberB1595-10
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PricePlease ask
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Size10 mg
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Alternative_name3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one, monohydrochloride
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DescriptionIvabradine hydrochloride is a highly selective open channel blocker that targets the mixed Na⁺/K⁺ inward “funny current” (If) carried by hyperpolarization-activated cyclic nucleotide gated (HCN) channels. It has antianginal activity. It lowers heart rate and reduces myocardial oxygen demand.
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CAS Number148849-67-6
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Structure AvailableYes
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Molecular FormulaC₂₇H₃₆N₂O₅·HCl
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Molecular Weight505.1
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesH₂O (~ 5mg/ml on warming)
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HandlingProtect from air and moisture
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Tag LineA highly selective open channel blocker
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00929899
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PubChem CID3045381
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SMILESCN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)CC3CC4=CC(=C(C=C34)OC)OC.Cl
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InChiInChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1
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InChi KeyHLUKNZUABFFNQS-ZMBIFBSDSA-N
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MSDS AvailableYes
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Gene target
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Short nameIvabradine Hydrochloride
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Alternative nameIvabradine Hydrochloride
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