Integrin linked ILK Antibody

• Catalog number
  PB9949
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Integrin linked ILK
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB
• Immunogen
  E.coli-derived human Integrin linked ILK recombinant protein (Position: M1-H203). Human Integrin linked ILK shares 99.5% amino acid (aa) sequence identity with both mouse and rat Integrin linked ILK.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Integrin linked ILK Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Integrin linked ILK Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
• Related articles
  1. "Entrez Gene: ILK integrin-linked kinase". 2. Fielding AB, Dobreva I, McDonald PC, Foster LJ, Dedhar S (Feb 2008). "Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization". The Journal of Cell Biology 180 (4): 681–9. 3. Melchior, C., Kreis, S., Janji, B., Kieffer, N. Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1. Biochim. Biophys. Acta 1575: 117-122, 2002.
• Gene Name
  ILK
• Protein Name
  Integrin-linked protein kinase
• Gene Full Name
  integrin linked kinase
• Synonyms
  HEL S 28 | ILK 1 | ILK-1 | ILK1 | ILK 2 | ILK-2 | ILK2 | ILK | Integrin linked Kinase | p59 | p59ILK | Q13418
• Uniprot ID
  Q13418
• Entrez GeneID
  3611
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Integrin   linked   ILK  
• Gene symbol
  ILK
• Short name
  Integrin linked ILK Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Integrin linked integrin-linked kinase (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  integrin-linked kinase, HEL-S-28 and ILK-1 and ILK-2 and P59 and p59ILK, ILK and IDBG-29381 and ENSG00000166333 and 3611, transferase activity, nuclei, Ilk and IDBG-204955 and ENSMUSG00000030890 and 16202, ILK and IDBG-634121 and ENSBTAG00000000696 and 540207

Gene info

• Identity
  HGNC:6040
• Gene
  ILK
• Long gene name
  integrin linked kinase
• Synonyms gene name
  • integrin-linked kinase
• GenBank acession
  • U40282
• Locus
  11p15.4
• Discovery year
  1997-05-22
• Entrez gene record
  3611
• Pubmed identfication
  • 8538749
• RefSeq identity
  • NM_004517
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000133407
• Locus Specific Databases
  • LRG_444

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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