Integrin alpha 2bAntibody

  • Catalog number
    bs-2636R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    Integrin alpha 2bPrimary Polyclonal Antibody
  • Also known as
    Integrin alpha 2bPAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    Integrin alpha 2b/CD41
  • Specificity
    This is a highly specific antibody against Integrin alpha 2b/CD41.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    370-420/1033
  • Subcellular location
    Extracellular
  • Source
    KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
  • Gene ID number
    16399
  • Swiss Prot
    Q9QUM0
  • Tested Applications
    IHC-P, IF(IHC-P)
  • Recommended dilutions
    IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    CD41; CD41B; GpIIb; AI172977; alphaIIb; Integrin alpha-IIb; GPalpha IIb; Platelet membrane glycoprotein IIb; Itga2b
  • Description
    The Anti-Integrin alpha 2b/CD41 is a α- or alpha protein sometimes glycoprotein present in blood.
  • Gene target
  • Short name
    Anti-Integrin alpha 2b/CD41
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    Integrin alpha 2bPolyclonal Antibody
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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