Integrin alpha 4/CD49d Antibody, ALEXA FLUOR 555

• Catalog number
  bs-0641R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  Integrin alpha 4/CD49d Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-Integrin alpha 4/CD49d PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Integrin alpha 4/CD49d
• Specificity
  This is a highly specific antibody against Integrin alpha 4/CD49d.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  584-609/1032
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 4
• Gene ID Number
  3676
• Swiss Prot
  P13612
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat, Rabbit
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  IA4; CD49D; Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; ITGA4
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• Description
  The Anti-Integrin alpha 4/CD49d is a α- or alpha protein sometimes glycoprotein present in blood.
• French translation
  anticorps

• Gene target
  Integrin   alpha   4/CD49d  
• Gene symbol
  ITGA4
• Short name
  Anti-Integrin alpha 4/CD49d
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  Integrin alpha 4/CD49d Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6140
• Gene
  ITGA4
• Long gene name
  integrin subunit alpha 4
• Synonyms gene
  • CD49D
• Synonyms gene name
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
• Synonyms
  • CD49d
• Synonyms name
  • antigen CD49D
  • alpha 4 subunit of VLA-4 receptor
• Locus
  2q31.3
• Discovery year
  1991-08-06
• Entrez gene record
  3676
• Pubmed identfication
  • 1537388
• Classification
  • CD molecules
  • Integrin alpha subunits
• VEGA ID
  OTTHUMG00000154212

MeSH Data

• Name
  CD4 Lymphocyte Count
• Concept
  Scope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
• Tree numbers
  • E01.370.225.500.195.107.595.500.150
  • E01.370.225.625.107.595.500.150
  • E05.200.500.195.107.595.500.150
  • E05.200.625.107.595.500.150
  • E05.242.195.107.595.500.150
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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