INCB-024360

• Catalog number
  9477-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (E)-N’-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(sulfamoylamino-1,2,5-oxadiazole-3-carboxamide); Epacadostat; INCB24360
• Description
  INCB-024360 is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor ( IC₅₀ = 10 nM); displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). Exhibits potent in vitro and in vivo immunomodulating and antineoplastic activities
• CAS Number
  1204669-58-8
• Structure Available
  Yes
• Molecular Formula
  C₁₁H₁₃BrFN₇O₄S
• Molecular Weight
  438.23
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• PubChem CID
  44608567
• PubChem CID Link
• SMILES
  C1=CC(=C(C=C1N/C(=C\2/C(=NON2)NCCNS(=O)(=O)N)/N=O)Br)F
• InChi
  InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16-17,19H,3-4H2,(H,15,20)(H2,14,22,23)/b11-9+
• InChi Key
  YPBKTZBXSBLTDK-PKNBQFBNSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  INCB-024360  
• Short name
  INCB-024360
• Alternative name
  INCB-024360

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