IL1RN, ID (Interleukin-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, INN=Anakinra, IL1RA, IL1F3)

• Catalog number
  MBS628152
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [IL1RN]
• Products_name_syn
  [Anti -IL1RN, ID (Interleukin-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, INN=Anakinra, IL1RA, IL1F3)]
• Other_names
  [interleukin-1 receptor antagonist protein isoform 4; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist protein; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); interleukin 1 receptor antagonist; ICIL-1RA; IL1 inhibitor]
• Other_gene_names
  [IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human IL1RN.
• Purity
  Purified Purified by ammonium sulfate precipitation.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The antagonist receptor ligand binding will be in contrast with agonist activity. MyBioSource produces more antagonist and receptor related products as 1. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  IL1RN   Interleukin-1   Receptor   Antagonist   Protein   IL-1ra   IL-1RN   IRAP   IL1   Inhibitor   ICIL-1RA   INN=Anakinra   IL1RA   IL1F3  
• Gene symbol
  IL1RN, IL6R, IL1F10, IL1A, IL1B, IL36G, IL25, IL22, IL18, IL37
• Short name
  IL1RN, ID (Interleukin-1 Receptor Antagonist Protein, IL-1ra, IL-1RN, IRAP, IL1 Inhibitor, ICIL-1RA, INN=Anakinra, IL1RA, IL1F3)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  interleukin 1 receptor anta this GO nist, ID (Interleukin-1 Receptor Antagonist Protein, Interleukin-1ra, Interleukin-1RN, IRAP, IL1 suppressor, ICIL-1RA, INN=Anakinra, IL1RA, IL1F3)
• Alternative to gene target
  interleukin 1 receptor anta this GO nist, DIRA and ICIL-1RA and IL-1ra and IL-1ra3 and IL-1RN and IL1F3 and IL1RA and IRAP and MVCD4, IL1RN and IDBG-66814 and ENSG00000136689 and 3557, interleukin-1, Extracellular, Il1rn and IDBG-142372 and ENSMUSG00000026981 and 16181, IL1RN and IDBG-634670 and ENSBTAG00000019665 and 281860

Gene info

• Identity
  HGNC:6000
• Gene
  IL1RN
• Long gene name
  interleukin 1 receptor antagonist
• Synonyms
  • IL1RA
  • ICIL-1RA
  • IL1F3
  • IRAP
  • IL-1RN
  • MGC10430
• Synonyms name
  • interleukin-1 receptor antagonist protein
  • intracellular interleukin-1 receptor antagonist
• GenBank acession
  • M55646
• Locus
  2q14.1
• Discovery year
  1990-11-20
• Entrez gene record
  3557
• Pubmed identfication
  • 1386337
  • 8432529
• RefSeq identity
  • NM_173841
• Classification
  • Interleukins
  • Interleukin receptors
• VEGA ID
  OTTHUMG00000131341
• Locus Specific Databases
  • LRG_188

Gene info

• Identity
  HGNC:6019
• Gene
  IL6R
• Long gene name
  interleukin 6 receptor
• Synonyms
  • CD126
  • IL-6R
  • IL-1Ra
  • IL6RA
  • gp80
• Synonyms name
  • membrane glycoprotein 80
  • interleukin 6 receptor subunit alpha
• GenBank acession
  • X12830
• Locus
  1q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  3570
• Pubmed identfication
  • 8428753
  • 12633863
• RefSeq identity
  • NM_000565
• Classification
  • CD molecules
  • Interleukin receptors
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000036073

Gene info

• Identity
  HGNC:15552
• Gene
  IL1F10
• Long gene name
  interleukin 1 family member 10
• Synonyms gene name
  • interleukin 1 family, member 10 (theta)
• Synonyms
  • FKSG75
  • IL-1HY2
  • IL-1F10
  • IL1-theta
  • MGC11983
  • MGC119832
  • MGC119833
• Synonyms name
  • FIL1- theta
  • interleukin-1 receptor antagonist FKSG75
• GenBank acession
  • AY026753
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  84639
• Pubmed identfication
  • 11747621
  • 11991723
  • 11991722
• RefSeq identity
  • NM_173161
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131339

Gene info

• Identity
  HGNC:5991
• Gene
  IL1A
• Long gene name
  interleukin 1 alpha
• Synonyms gene
  • IL1
• Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
• Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
• GenBank acession
  • M28983
• Locus
  2q14.1
• Discovery year
  2001-06-22
• Entrez gene record
  3552
• Pubmed identfication
  • 8188271
  • 2989698
• RefSeq identity
  • NM_000575
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131315

Gene info

• Identity
  HGNC:5992
• Gene
  IL1B
• Long gene name
  interleukin 1 beta
• Synonyms
  • IL1F2
  • IL-1B
  • IL1-BETA
• GenBank acession
  • M15330
• Locus
  2q14.1
• Discovery year
  1989-03-31
• Entrez gene record
  3553
• Pubmed identfication
  • 2954882
  • 2989698
• RefSeq identity
  • NM_000576
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131344

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

Gene info

• Identity
  HGNC:5986
• Gene
  IL18
• Long gene name
  interleukin 18
• Synonyms gene name
  • interleukin 18 (interferon-gamma-inducing factor)
• Synonyms
  • IGIF
  • IL1F4
  • IL-1g
  • IL-18
• Synonyms name
  • interferon-gamma-inducing factor
• GenBank acession
  • U90434
• Locus
  11q23.1
• Discovery year
  1997-07-25
• Entrez gene record
  3606
• Pubmed identfication
  • 7477296
  • 9693051
• RefSeq identity
  • NM_001562
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000167006

Gene info

• Identity
  HGNC:15563
• Gene
  IL37
• Long gene name
  interleukin 37
• Synonyms gene
  • IL1F7
• Synonyms gene name
  • interleukin 1 family, member 7 (zeta)
• Synonyms
  • FIL1
  • FIL1Z
  • FIL1(ZETA)
  • IL-1H4
  • IL-1RP1
  • IL-1F7
• Synonyms name
  • interleukin 1, zeta
  • interleukin-1 homolog 4
  • interleukin-1-related protein
• GenBank acession
  • AF201832
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27178
• Pubmed identfication
  • 10625660
  • 10512743
  • 12496389
• RefSeq identity
  • NM_014439
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131345

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