IL-7R/CD127 (Phospho-Tyr449) Antibody

Applications

WB IF ELISA
Source

Rabbit
Reactivity

H, M
MW kDa

51 kDa
Target Modification

Phospho
Modification Sites

H:Y449 M:Y449
Immunogen

The antiserum was produced against synthesized peptide derived from human IL-7R/CD127 around the phosphorylation site of Tyr449.
Immunogen Range

410-459
Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Specificity

IL-7R/CD127 (Phospho-Tyr449) Antibody detects endogenous levels of IL-7R/CD127 only when phosphorylated at Tyr449.
Gene ID

3575
Swiss Prot No

P16871
OMIM No

126200/146661/608971
Unigene No

Hs.591742/Hs.635723
NCBI Gene Symbol

IL7RA
Synonyms

CD127 antigen; CDw127; IL-7R alpha; IL7RA; interleukin-7 receptor alpha chain
Storage Stability

Stable at -20°C for at least 1 year.
Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality

Polyclonal
Concentration

1 mg/ml
Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation

anticorps

Identity

HGNC:6024
Gene

IL7R
Long gene name

interleukin 7 receptor
Synonyms
- CD127
- IL7RA
GenBank acession
- M29696
Locus

5p13.2
Discovery year

1991-08-07
Entrez gene record

3575
Pubmed identfication
- 2317865
Classification
- Interleukin receptors
- Fibronectin type III domain containing
- CD molecules
VEGA ID

OTTHUMG00000090791
Locus Specific Databases
- IL7Rbase: Mutation registry for Interleukin-7 receptor α deficiency
- LRG_74

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Identity

HGNC:5981
Gene

IL17A
Long gene name

interleukin 17A
Synonyms gene
- CTLA8
- IL17
Synonyms gene name
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Synonyms
- IL-17A
- IL-17
Synonyms name
- cytotoxic T-lymphocyte-associated protein 8
GenBank acession
- U32659
Locus

6p12.2
Discovery year

1993-10-25
Entrez gene record

3605
Pubmed identfication
- 8390535
RefSeq identity
- NM_002190
Classification
- Interleukins
VEGA ID

OTTHUMG00000014840
Locus Specific Databases
- LRG_1223

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

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