IL-36gamma Recombinant Protein

  • Catalog number
    40-603
  • Price
    Please ask
  • Size
    0.002 mg, 0.01 mg
  • About recombinant protein
    The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.
  • Other name of the recombinant
    IL1E, IL1F9, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2, IL1E, UNQ2456/PRO5737, Interleukin-36 gamma, IL-1-related protein 2
  • Recombinant in
    E. coli
  • SEQUENCE
    SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND
  • Keep at
    The lyophilized IL-36gama recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-36gama is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-36gama recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
  • Rec PROTEIN GI
    514388113
  • Accession nr
    NP_001265497.1
  • Pureity
    Greater than 95% by SDS-PAGE gel and HPLC analyses.
  • About
    This product is for research use only.
  • Protein s origin
    Human
  • Vial
    Lyophilized
  • NCBI ID
    56300
  • Gene name
    interleukin 36, gamma
  • Source
    Homo sapiens
  • Uniprot
    Q9NZH8
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    IL36G
  • Short name
    IL-36gamma Recombinant Protein
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    Interleukin-36gamma Rec. Protein
  • Alternative technique
    rec
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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