IL-36gamma Recombinant Protein
-
Catalog number
40-603
-
Price
Please ask
-
Size
0.002 mg, 0.01 mg
-
-
About recombinant protein
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.
-
Other name of the recombinant
IL1E, IL1F9, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2, IL1E, UNQ2456/PRO5737, Interleukin-36 gamma, IL-1-related protein 2
-
Recombinant in
E. coli
-
SEQUENCE
SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND
-
Keep at
The lyophilized IL-36gama recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-36gama is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-36gama recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
-
Rec PROTEIN GI
514388113
-
Accession nr
NP_001265497.1
-
Pureity
Greater than 95% by SDS-PAGE gel and HPLC analyses.
-
About
This product is for research use only.
-
Protein s origin
Human
-
Vial
Lyophilized
-
NCBI ID
56300
-
Gene name
interleukin 36, gamma
-
Source
Homo sapiens
-
Uniprot
Q9NZH8
-
-
-
Additional source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
IL36G
-
Short name
IL-36gamma Recombinant Protein
-
Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Alternative name
Interleukin-36gamma Rec. Protein
-
Alternative technique
rec
-
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 36 gamma
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 9
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products