IL-36beta Recombinant Protein

• Catalog number
  40-602
• Price
  Please ask
• Size
  0.002 mg, 0.01 mg

• About recombinant protein
  The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
• Other name of the recombinant
  FIL1, FIL1H, IL1F8, IL1H2, IL-1F8, IL-1H2, IL1-ETA, FIL1-(ETA), FILI-(ETA), Interleukin-36 beta, FIL1 eta, IL-1 eta
• Recombinant in
  E. coli
• SEQUENCE
  MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE
• Keep at
  The lyophilized IL-36beta recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-36beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-36beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  20070252
• Accession nr
  NP_055253.2
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  27177
• Gene name
  interleukin 36, beta
• Source
  Homo sapiens
• Uniprot
  Q9NZH7
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-36beta   Protein  
• Gene symbol
  IL36B
• Short name
  IL-36beta Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Interleukin-36beta Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:15564
• Gene
  IL36B
• Long gene name
  interleukin 36 beta
• Synonyms gene
  • IL1F8
• Synonyms gene name
  • interleukin 1 family, member 8 (eta)
• Synonyms
  • FIL1
  • IL-1H2
  • IL-1F8
  • FILI-(ETA)
  • IL1-ETA
  • IL1H2
  • MGC126880
  • MGC126882
• GenBank acession
  • AF201833
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27177
• Pubmed identfication
  • 10625660
  • 10512743
  • 16646978
• RefSeq identity
  • NM_014438
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131338

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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