IL-12 beta Antibody, Biotin Conjugated

• Catalog number
  bs-10641R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  IL-12 beta Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  IL-12 beta
• Specificity
  This is a highly specific antibody against IL-12 beta.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  220-255/328
• Subcellular location
  Secreted
• Gene ID number
  3593
• Swiss Prot
  P29460
• Tested applications
  WB
• Recommended dilutions
  WB(1:100-1000)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; Interleukin-12 subunit beta; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; IL12B
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  IL-12   beta   Conjugated  
• Gene symbol
  IFNLR1, PIRC55, PIRC54, PIRC53, PIRC57, PIRC56, SNORD116-12, IGHV3OR16-12, SNORD114-12
• Short name
  Anti-IL-12 beta
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-IL-12 beta PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18584
• Gene
  IFNLR1
• Long gene name
  interferon lambda receptor 1
• Synonyms gene
  • IL28RA
• Synonyms gene name
  • interleukin 28 receptor, alpha
  • interleukin 28 receptor, alpha (interferon, lambda receptor)
  • interferon, lambda receptor 1
• Synonyms
  • CRF2/12
  • IFNLR
  • IL-28R1
• GenBank acession
  • AY129153
• Locus
  1p36.11
• Discovery year
  2002-12-02
• Entrez gene record
  163702
• RefSeq identity
  • NM_170743
• Classification
  • Interferon receptors
• VEGA ID
  OTTHUMG00000003036

Gene info

• Identity
  HGNC:37559
• Gene
  PIRC55
• Long gene name
  piwi-interacting RNA cluster 55
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313792
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37558
• Gene
  PIRC54
• Long gene name
  piwi-interacting RNA cluster 54
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313815
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37557
• Gene
  PIRC53
• Long gene name
  piwi-interacting RNA cluster 53
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313861
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37561
• Gene
  PIRC57
• Long gene name
  piwi-interacting RNA cluster 57
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313930
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37560
• Gene
  PIRC56
• Long gene name
  piwi-interacting RNA cluster 56
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313862
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33078
• Gene
  SNORD116-12
• Long gene name
  small nucleolar RNA, C/D box 116-12
• Synonyms
  • HBII-85-12
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033424
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003327
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5636
• Gene
  IGHV3OR16-12
• Long gene name
  immunoglobulin heavy variable 3/OR16-12 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-12
• Synonyms
  • IGHV3/OR16-12
• GenBank acession
  • Z29609
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28304
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176355

Gene info

• Identity
  HGNC:33000
• Gene
  SNORD114-12
• Long gene name
  small nucleolar RNA, C/D box 114-12
• Synonyms
  • 14q(II-12)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767590
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003205.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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