IL-27 / EBI-3, murine recombinant

  • Catalog number
    4377-100
  • Price
    Please ask
  • Size
    100 ug
  • Synonyms
    Epstein-Barr virus induced 3, EBI3
  • Alternative_names
    Epstein-Barr virus induced 3, EBI3
  • Description
    A cytokine regulating the activity of B- and T-lymphocytes
  • Recombinant
    Yes
  • Source
    E. coli
  • Purity by SDS PAGE
    ≥90%
  • Assay
    SDS-PAGE
  • Purity
    ≥90%
  • Biological activity
    Assay data for mouse recombinant EBI-3 is based upon qualitative binding to anti-EBI-3 antibody.
  • Molecular Weight
    22.9 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Lyophilized from 10 mM Sodium citrate, pH 3.
  • Reconstitution Instructions
    When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 – 0.5 mg/ml, which can be further diluted into other aqueous solutions.
  • Background Information
    Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant Mouse EBI is a non-glycosylated polypeptide chain consisting of 207 amino acids with a molecular weight of 22,900 Da.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    IL-27   EBI-3   murine  
  • Gene symbol
    IL17D, IL27, MYDGF, SNORD115-27, EBI3, IGKV1D-27, ERVK-27, ERVW-27, RNVU1-27, IGHV7-27
  • Short name
    IL-27 / EBI-3, murine recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    Interleukin-27 / EBI-3, murine Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 1D-27 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 1D-27
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin kappa locus at 2p11.2
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    endogenous retrovirus group K member 27
  • Synonyms gene name
    • endogenous retrovirus group K, member 27
  • GenBank acession
  • Locus
  • Discovery year
    2014-01-03
  • Pubmed identfication
Gene info
  • Identity
  • Gene
  • Long gene name
    endogenous retrovirus group W member 27
  • Synonyms gene name
    • endogenous retrovirus group W, member 27
  • GenBank acession
  • Locus
  • Discovery year
    2013-10-21
Gene info
  • Identity
  • Gene
  • Long gene name
    RNA, variant U1 small nuclear 27
  • Locus
  • Discovery year
    2019-07-26
  • Classification
    • Variant U1 small nuclear RNAs
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 7-27 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable 7-27
    • immunoglobulin heavy variable 7-27 pseudogene
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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